Lipid metabolism — Flashcards

Biliary tract diseases (e.g. PBC, PSC) are associated with _____ serum cholesterol

Increased levels of cholesterol inside the hepatocyte leads to increased activity of the enzyme _____

Primary carnitine deficiency is characterized by muscle weakness and hypotonia, which is provoked by prolonged _____ (especially if fasting)

Enzyme Replacement Therapy for _____ disease requires replacement of IV Glucocerebrosidase

Refsum disease is a(n) autosomal recessive metabolic disorder caused by defective _____-oxidation

Fatty acids, from triglyceride breakdown, are broken down into acetyl CoA via the process of _____

Which vitamins are fat-soluble? _____

Hint: 4

The Peroxisome is unique in that it performs α-oxidation to break down _____

What is the purpose of converting cholesterol into cholesterol ester? _____

Fat-soluble deficiencies may occur with syndromes that cause _____ (e.g. cystic fibrosis and sprue)