Disorders of lipid metabolism — Flashcards

What substrate accumulates in the lysosomes of a patient with Niemann Pick disease? _____

Which serum lipoprotein is elevated in type IV familial dyslipidemia? _____

Abetalipoproteinemia is associated with malabsorption due to defective _____ formation, which requires apoB-48

Which lipid transport enzyme is responsible for the degradation of triglycerides in the chylomicrons and VLDLs? _____

Which lysosomal storage disease is characterized by a cherry red spot on the macula and hepatosplenomegaly? _____

Which three lipoproteins is apoprotein B-100 found on? _____

_____ is associated with absent plasma VLDL and LDL, which require apoB-100

Which serum lipoprotein is elevated in type IIa familial dyslipidemia? _____

lipoamide

Where does fatty acid oxidation take place?