Pharmacokinetics and Pharmacodynamics — Flashcards

Flashcard 1: What formula is used to calculate loading dose? _____

Answer:

Flashcard 2: What formula is used to calculate half-life in first-order elimination kinetics? _____

Answer:

Flashcard 3: What formula is used to estimate volume of distribution (Vd)? _____

Answer:

Flashcard 4: What formula is used to calculate maintenance dose? _____

Answer:

Flashcard 5: Sketchy Pharmacology: Neuro/Psych Does the blue curve represent an inhaled anesthetic with a high or low blood solubility? _____

Answer: Low (quickly saturated, e.g. N2O)

Flashcard 6: Any medications, blood products, and fluids can_____ be administered through Intraosseous route

Answer:  

Flashcard 7: Sketchy Pharmacology: Neuro/Psych Does the red curve represent an inhaled anesthetic with a high or low blood solubility? _____

Answer: High (slowly saturated, e.g. halothane)

Flashcard 8: in OPV _____ serotype has max efficiency and intestinal absorption

Answer: P2

Extra: 

Flashcard 9: Phenytoin follows _____-order kinetics at lower concentrations. As the concentration increases, the elimination changes to zero-order kinetics.

Answer: first

Flashcard 10: Aminoglycosides exert _____-dependent killing and a long post-antibiotic effect

Answer: concentration