Drugs for Gastrointestinal Diseases — Flashcards

Loperamide is a _____ agonist that does not cross the BBB, therefore there is no analgesia and low potential for addiction

Guanylate cyclase-C agonist indicated in _____ constipation is linaclotide.

Hint: acute/chronic

GI _____ is a PGE1 analog that may be used to prevent NSAID-induced peptic ulcers

_____ is a non-toxic bile acid used in the treatment of early primary biliary cholangitis (formerly primary biliary cirrhosis).

Ondansetron is used to treat _____ or post-operative induced nausea and vomiting

Polymerization of _____ occurs only at an acidic pH by crosslinking of the molecules, which helps in gastic ulcer protection

_____ is indicated with pyridoxine to reduce mild to moderate nausea and vomiting in the early stages of pregnancy

**Ursodeoxycholic Acid** is a secondary bile acid used for the dissolution of _____ gallstones in patients with contraindications to surgery.

Sulfasalazine is metabolized by _____ into the active component (mesalamine) which is used to treat the colitis aspects of IBD

Misoprostol can be clinically used to treat gastric ulcers as at _____ doses it inhibits secretion of gastric acid