Laxatives and Purging Agents — Flashcards

_____ is indicated for the reversal of opioid-induced constipation in patients on chronic opioid therapy.

Which drug is preferred for chronic idiopathic constipation and constipation-predominant irritable bowel syndrome?_____

Guanylate cyclase-C agonist indicated in _____ constipation is linaclotide.

Hint: acute/chronic

Bile acid resins frequently cause GI side effects, such as _____ and bloating

Bile acid resins can lead to _____, which may impair the absorption of fat-soluble vitamins (A, D, E, K)

_____ is CCK-B receptor antagonist used in treatment of gastrinoma/Zollinger-Ellison Syndrome

_____ is a gastroprokinetic agent which acts as a 5-HT4 receptor agonist

_____ is made of two molecules of 5-ASA used in the treatment of Inflammatory Bowel Disease

Because PGE1 is involved in physiological responses of the gut mucosa and the uterine smooth muscle, Misoprostol can cause _____ as well as uterine contractions

_____ (macrolide) can bind GI motilin receptors, increasing GI motility and causing diarrhea