Drugs for Gastrointestinal Diseases — Flashcards

When proton pump inhibitors are unable to control gastric acid secretion, _____ (a long acting somatostatin analog) may be of use in treating gastrinomas

H2 receptor antagonists are especially effective at reducing _____ secretion of acid, however, they only have modest impact on meal-stimulated secretion of acid

Anti-Emetics: _____ antagonizes NK1 receptors in the area postrema; it is used to treat chemotherapy-induced vomiting.

Anti-Emetics ('Vomitorium'): _____ antagonizes the 5-HT3 receptor on vagal afferents in the GI tract

GI (Antidiarrheals): _____ is a mu-opioid agonist that does cross the BBB, therefore it is combined with atropine to prevent abuse.

A major adverse effect of orlistat is _____, which may lead to decreased absorption of fat-soluble vitamins

In the treatment of **Cystic Fibrosis**, _____ is a mixture of pancreatic enzymes used to treat exocrine pancreatic insufficiency.

Histamine, from ECL cells, activates _____ receptors (coupled to Gs) on the basolateral membrane of parietal cells

Loperamide is a _____ agonist that does not cross the BBB, therefore there is no analgesia and low potential for addiction

Guanylate cyclase-C agonist indicated in _____ constipation is linaclotide.

Hint: acute/chronic