Antimicrobial Agents — Flashcards

The most serious adverse effect of _____ use is optic neuritis,characterized by loss of visual acuity and red-green colorblindness (TB drug)

Persons in close contact with an individual with Neisseria meningitidis infection are given prophylactic _____, ciprofloxacin or ceftriaxone

_____ inhibits the enzyme dihydrofolate reductase in protozoa (pyrimidine synthesis)

Treatment of falciparum malaria during pregnancy:2nd and 3rd trimester: _____ in North-Eastern states and ACT-SP in other states.

NRTIs are incorporated into _____ DNA, causing premature chain termination

Resistance of penicillins comes from production of _____ that cleave the β-lactam ring, or changes to penicillin binding proteins (confers methicillin resistance in MRSA).

Anti-staph penicillins include _____, nafcillin, and dicloxacillin

_____ are a class of antifungals that inhibit the enzyme 14-demethylase

_____ is a macrolide antibotic that can be used in prophylaxis of Mycobacterium avium complex in patients with CD4 count < 50.

_____ are a class of antifungals that inhibit the enzyme 1,3-β-glucan synthase