Antimicrobial Agents — Flashcards

Flashcard 211: The fluoroquinolones _____ and moxifloxacin can be used to treat Mycoplasma pneumoniae, Legionella pneumophila (atypical pneumonia)

Answer: levofloxacin

Flashcard 212: _____ is a macrolide antibotic that can be used in prophylaxis of Mycobacterium avium complex in patients with CD4 count < 50.

Answer: Azithromycin

Flashcard 213: Which two classes of antifungals inhibit synthesis of ergosterol from squalene? _____

Answer: Allylamines and Benzylamines

Flashcard 214: Fluoroquinolones inhibit _____ and Topoisomerase IV.

Answer: DNA gyrase (Topoisomerase II)

Extra: In Gram-negative bacteria, DNA gyrase is the primary target. In Gram-positive bacteria, topoisomerase IV is the primary target.

Flashcard 215: Patients with Pseudomonas pneumonia are treated with: _____ + fluoroquinolone OR aminoglycoside

Answer: Antipseudomonal beta-lactam

Flashcard 216: What is the treatment (2) of local, cutaneous tinea infections (azoles)? _____

Answer: Clotrimazole and Miconazole

Flashcard 217: The most serious adverse effect of _____ use is optic neuritis,characterized by loss of visual acuity and red-green colorblindness (TB drug)

Answer: ethambutol

Flashcard 218: Treatment of Streptococcus pneumoniae includes _____ and ceftriaxone (3rd gen. cephalosporin)

Answer: azithromycin (macrolides)

Flashcard 219: Which two antibiotics are used to treat nosocomial MRSA infections? _____ and _____

Answer: Vancomycin

Flashcard 220: _____ solution contains chloramphenicol, oestradiol and vitamin D2.

Answer: Kemicetine antiozaena