Sulfonamides and Trimethoprim — Flashcards

The fluoroquinolones _____ and moxifloxacin can be used to treat Streptococcus pneumoniae, Haemophilus spp. (community-acquired pneumonia)

Cephalosporins that contain a _____ group can cause hypoprothrombinemia (factor II) and thereby bleeding problems.

_____ and ofloxacin have the maximum bioavailability among fluoroquinolones.

Hypersensitivity reactions are common with Sulfa drug use; result in fever, hypotension, _____ and rash

_____ inhibits the enzyme dihydrofolate reductase in prokaryotes (pyrimidine synthesis)

_____ inhibits the enzyme dihydrofolate reductase in protozoa (pyrimidine synthesis)

_____ are commonly used in patients that cannot tolerate aminoglycosides due to renal insufficiency.

_____ and Pneumocystis jirovecii are treated prophylactically in HIV patients with Trimethoprim-sulfamethoxazole (TMP-SMX)

Which step ([A] - [E]) of Bacterial Protein Synthesis do Aminoglycosides inhibit? _____

Which step ([A] - [E]) of Bacterial Protein Synthesis does Clindamycin inhibit? _____