Anticancer Drugs — Flashcards

Vitamin _____ may be used to treat measles and acute promyelocytic leukemia (APML)

Cyclophosphamide attaches an alkyl group to the _____ of guanine

Platinum based antineoplastics are indicated for various carcinomas that affect the _____ system, Reproductive system, and Respiratory system

_____ and sorafenib are small molecules that inhibit the VEGFR tyrosine kinase

_____ is a MEK inhibitor that is often co-administered with vemurafenib.

The two chimeric antitumor monoclonal antibodies are _____ and cetuximab

Cyclophosphamide can be used as an immunosuppresant for the treatment of _____ nephritis, as well as for systemic vasculitides

Eribulin is a chemotherapeutic that works by inhibiting microtubule _____ and sequestering tubulin into nonfunctional aggregates

As two classes of antineoplastic agents that modulate microtubule structure, the distinction lies in that vinca-alkaloids prevent microtubule _____ whereas taxanes prevent microtubule disassembly

Because Her2/Neu is expressed on the _____, Trastuzumab can cause Heart failure