Anticancer Drugs — Flashcards

Bevacizumab has an increased risk of _____ and thrombotic events

Which chemotherapeutic drugs are associated with hemorrhagic cystitis with acrolein in urine?_____

Because sorafenib targets VEGF, areas that are highly vascularized will be affected such as the _____ and the kidney

Intercalation of Anthracyclines into DNA inhibits the progression of Topoisomerase II and induces eviction of histones

The main acute side effect of Tisagenlecleucel is _____ while a potential long term risk is the potential for insertional mutagenesis

Which two solid tumors specifically can etoposide and teniposide (topoisomerase II inhibitors) be used to treat?_____, Small cell lung carcinoma

Etoposide and teniposide can result in _____-suppression and immuno-suppression

Acute promyelocytic leukemia is treated with _____, a vitamin A derivative, as well as arsenic

_____ and olaparib are PARP inhibitors approved for the treatment of advanced ovarian cancer.

Cladribine is activated primarily in _____, and works by inhibiting the enzyme adenosine deaminase (ADA)