Neoplasia — Flashcards

The HER2/neu proto-oncogene encodes for the HER2 receptor, which when activated leads to cell _____This is a growth factor receptor found commonly in breast cancer

ER/PR-_____, HER2-negative cancers is the most common subtype of breast cancer in individuals who inherit germline mutations in BRCA2

A translocation of _____ from chromosome 11 to 14 results in overexpression and ultimately Mantle cell lymphoma

_____ is a cystic salivary gland tumor with abundant lymphocytes and germinal centers

Luminal B subtype of breast cancer can be ER/PR _____ve and HER2 +/-ve, with high Ki67

Pleomorphic adenoma is a slow growing _____ tumor that is potentially malignant

Which type(s) of cells line the fibrovascular projections of a papillary carcinoma of the breast? _____

Adenomatous polyps with a _____ histology have less malignant potential than villous histology (tubular or villous)

10% to 15% of individuals do not have the elevation of the CA 19-9 level in CA pancreas, a finding that has been associated with blood _____ antigennegative status.

Borderline tumors have _____ prognosis than clearly malignant tumors, but still carry metastatic potential