Neoplasia — Flashcards

_____ cystadenocarcinoma may present with pseudomyxoma peritonei, which is an intraperitoneal accumulation of mucinous material, usually from a GI, ovarian, appendiceal tumor

The t(_____,14) translocation results in overexpression of Cyclin D1, which promotes the G1/S transition in the cell cycle, facilitating neoplastic proliferation

Ovarian serous adenocarcinoma is CK 7 _____ and CK 20 negative

Tumors that cause a _____ can be remembered with the mnemonic: Paraneoplastic rise to high hematocrit levelsPheochromocytomaRenal cell carcinomaHepatocellular CarcinomaHemangioblastomaLeiomyoma

A translocation of _____ from chromosome 11 to 14 results in overexpression and ultimately Mantle cell lymphoma

Invasive carcinomas become metastatic when they invade the _____ or blood

The HER2/neu proto-oncogene encodes for the HER2 receptor, which when activated leads to cell _____This is a growth factor receptor found commonly in breast cancer

ER/PR-_____, HER2-negative cancers is the most common subtype of breast cancer in individuals who inherit germline mutations in BRCA2

Ovarian carcinoma is associated with '_____', which occurs from seeding of the peritoneum with layers upon layers of tumor cell growth

_____ carcinoma, a subtype of invasive ductal carcinoma, is characterized by cancer within dermal lymphatics