Neoplasia — Flashcards

Smooth muscle can give rise to a _____ (benign) and leiomyosarcoma (malignant)

Histopathology of mesothelioma will show tumor cells with numerous, long slender _____ and abundant tonofilaments

Common sites of metastasis from lung cancer include the _____, brain, bone, and liver

Esophageal carcinoma in the middle third of the esophagus spreads to _____, tracheobronchial, or paratracheal lymph nodes

Which four carcinomas route hematogenously?_____ChoriocarcinomaRenal cell carcinomaHepatocellular carcinoma

Most common _____ tumor of salivary gland in children is hemangioma

Hint: benign/malignant

MEN 1 is associated with mutation of the _____ gene (menin), which is a tumor suppressor gene found on chromosome 11

HPV encodes E6 and E7 which promotes proteolysis of _____ and Rb.

_____ cystadenocarcinoma may present with pseudomyxoma peritonei, which is an intraperitoneal accumulation of mucinous material, usually from a GI, ovarian, appendiceal tumor

The t(_____,14) translocation results in overexpression of Cyclin D1, which promotes the G1/S transition in the cell cycle, facilitating neoplastic proliferation