Neoplasia — Flashcards

IgA antibodies of _____ of EBV are highly specific for nasopharyngeal cancer

Hint: antigen

HER2 (c-erbB2) is an _____ receptor found in certain types of breast and gallbladder carcinoma

Blood vessels can give rise to a _____ (benign) and angiosarcoma (malignant)

Adenocarcinoma of the bladder may arise from _____, which is a columnar metaplasia in response to chronic inflammation

Transitional cell (urothelial) carcinoma via the _____ pathway is associated with early p53 mutations

Luminal A subtype of breast cancer is usually ER/PR _____ve and HER2 -ve, with low Ki-67 index.

When performing Immunohistochemistry; Chromogranin A, Synaptophysin, NCAM (CD56), Neuron Specific Enolase (NSE) can all be used to identify _____ and Neuronal tumors

Lynch syndrome is associated with increased risk for _____, endometrial, ovarian, and skin cancers

Tumor cells can attach to _____ and destroy the basement membrane (type IV collagen) via collagenase

MEN 1 is associated with mutation of the _____ gene (menin), which is a tumor suppressor gene found on chromosome 11