Neoplasia — Flashcards

Flashcard 231: HER2 overexpression is associated with _____ survival in breast cancer

Answer: poorer

Flashcard 232: The most common EBV-associated tumor is _____ malignancy.

Answer: gastric

Flashcard 233: In breast cancer IHC, a HER2 score of 3+ is interpreted as _____.

Answer: Positive

Flashcard 234: What is the most common variant of rectal carcinoma?_____

Answer: AdenoCA

Flashcard 235: _____-acting carcinogens require metabolic conversion to become carcinogenic

Answer: Indirectly

Flashcard 236: WHO Classification of Nasopharyngeal Carcinoma (NPC): Type _____ is the non-keratinizing undifferentiated variant.

Answer: III (Type 3)

Extra: The WHO classification for Nasopharyngeal Carcinoma (NPC) is as follows: - **Type I**: Keratinizing squamous cell carcinoma. - **Type II**: Non-keratinizing differentiated carcinoma. - **Type III**: Undifferentiated carcinoma (includes lymphoepithelioma variant). Type III is the most common variant, is most strongly associated with EBV, and is the most radiosensitive.

Flashcard 237: What is the most important prognostic factor for Wilms tumor?_____

Answer: Anaplastic histology

Flashcard 238: What are the 3 types of RAS oncogenes?_____

Answer: K-RAS, N-RAS and H-RAS

Flashcard 239: Non-seminomatous germ cell tumors use the _____ route to metastasize

Answer: hematogenous

Flashcard 240: _____ hemangiomas are the most common type of hemangiomas

Answer: Capillary