Neoplasia Indian Medical PG Flashcards - Medical Study Cards
Master Neoplasia with OnCourse flashcards. These spaced repetition flashcards are designed for medical students preparing for NEET PG, USMLE Step 1, USMLE Step 2, MBBS exams, and other medical licensing examinations.
Neoplasia Flashcard Deck - 10 Cards
Flashcard 211: Woodworkers are more likely to develop _____ variety of sinonasal carcinoma
Answer: adenocarcinoma (histological)
Flashcard 212: Hepatoblastoma has been associated with the _____ syndrome
Answer: familial adenomatous polyposis (FAP) (cancer)
Flashcard 213: In Wilms tumour, metastasis to the _____ occurs early
Answer: lungs
Flashcard 214: _____ is associated with carcinoma of the Ampulla of Vater of the CBD
Answer: Familial adenomatous polyposis (Cancer syndrome)
Flashcard 215: WHO classification of Nasopharyngeal Carcinoma (NPC): Type III is _____ carcinoma
Answer: Undifferentiated (Lymphoepithelioma)
Extra: WHO Classification of Nasopharyngeal Carcinoma (NPC):
- Type I: Keratinizing Squamous Cell Carcinoma (SCC)
- Type II: Non-keratinizing SCC
- Type III: Undifferentiated carcinoma (most common type, strongly associated with EBV)
Note: Basaloid SCC is a rare variant recognized in newer WHO classifications but is distinct from the traditional Type III (undifferentiated) category.
Flashcard 216: The biologic behaviour of chondrosarcoma directly correlates with the _____ of tumor
Answer: grade
Flashcard 217: Two-thirds of fibroadenomas harbor driver mutations in _____ gene
Answer: MED12
Flashcard 218: Angiosarcoma and hemangiopericytoma are _____ grade neoplasms
Answer: malignant
Flashcard 219: Tumors confined to the muscle layer, no lymph node invasion are classified as _____ according to Modified Duke's classification
Answer: B1
Extra: Modified Duke's (Astler-Coller) classification for Colorectal Cancer:
- **A**: Limited to mucosa
- **B1**: Extending **into** muscularis propria (nodes negative)
- **B2**: Extending **through** muscularis propria into the serosa/subserosa (nodes negative)
- **C1**: Extending into muscularis propria (nodes positive)
- **C2**: Extending through muscularis propria (nodes positive)
- **D**: Distant metastasis
Since the tumor is "confined to" the muscle layer, it is classified as B1.
Flashcard 220: What is the most common visceral organ involved in metastatic spread of neoplasms?
Answer: Liver
Extra: The most common **site** of metastasis overall is the **lymph nodes**.
The most common **visceral organ** involved in distant (hematogenous) metastasis is the **liver**, followed by the **lungs**.
*Note: The liver is frequently involved because it receives blood from both the systemic circulation and the portal system.*
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