Neoplasia — Flashcards

ER/PR-_____, HER2-negative breast cancer is the most common subtype in individuals who inherit germline mutations in BRCA1

_____ carcinoma of the lung may secrete the hormone beta-hCG

2-Naphthylamine is a carcinogenic aromatic amine found in _____ associated with Transitional Cell Carcinoma of the Bladder

Wilms tumor is caused by "loss of function" mutations of tumor suppression genes _____ or WT2 on chromosome 11

_____ is a malignant salivary gland tumor composed of mucinous and squamous cells. It is most commonly associated with the t(11;19) translocation creating the CRTC1-MAML2 fusion protein.

Gorlin syndrome is associated with a high risk of _____ carcinoma and medulloblastoma.

Chronic irritation of the bladder can cause _____ metaplasia, which may progress to squamous cell carcinoma

Her2 enriched subtype of breast cancer usually has a _____ Ki67

Peutz-Jeghers-Touraine syndrome is due to loss-of-function mutation of _____ gene

In breast cancer IHC scoring, a result of 1+ is interpreted as HER2 ______.