Neoplasia — Flashcards

_____ is a non-invasive breast cancer characterized by dyscohesive cells due to lack of E-cadherin protein

One subtype of invasive ductal carcinoma (breast) is _____ carcinoma, which is characterized by large, high-grade malignant cells growing in sheets with lymphocytic infiltrate

_____ tumor is metastatic mucinous tumor that involves both ovaries; most commonly due to metastatic gastric carcinoma (diffuse type)

_____ subtype is a triple-negative breast cancer with low expression of E-cadherin, with a poor prognosis

Uncertain or low malignant potential in GIST is determined by _____ cm size; >5 mitoses/50 HPF

Wilms tumor is caused by "loss of function" mutations of tumor suppression genes _____ or WT2 on chromosome 11

_____ is a malignant salivary gland tumor composed of mucinous and squamous cells *what is the most common mutation?

Gorlin syndrome is associated with a high risk of _____ carcinoma and medulloblastoma.

Chronic irritation of the bladder can cause _____ metaplasia, which may progress to squamous cell carcinoma

A follicular lymphoma due to Bcl-2 overexpression results from a _____ mutation