Neoplasia — Flashcards

_____ lung carcinoma may produce the anterior pituitary hormone ACTH leading to Cushing syndrome

_____ lung carcinoma arises from neuroendocrine (Kulchitsky) cells, which are small, dark blue cells

_____ is a tumor suppressor gene whose product inhibits hypoxia inducible factor 1- (HIF-1)

_____ syndrome is a combination of: 1. Wilms tumor 2. Early-onset nephrotic syndrome 3. Male pseudohermaphroditism (gonadal dysgenesis)

Metastasis oncogenes such as _____ and TWIST encode transcription factors whose primary function is to promote epithelial-to-mesenchymal transition (EMT).

_____ is a malignant germ cell tumor composed of mononuclear cytotrophoblasts and multinuclear syncytiotrophoblasts, but with absent villi

The cells of _____ tumors contain amine precursor uptake decarboxylase (APUD)

Is angiofibroma benign or malignant?_____

Following APC mutation (adenoma-carcinoma sequence), _____ mutations lead to polyp formation (adenoma)

Which immunohistochemical markers are seen in embryonal carcinoma?_____ and CD30