Neoplasia — Flashcards

_____ lung carcinoma arises from neuroendocrine (Kulchitsky) cells, which are small, dark blue cells

_____ is a tumor suppressor gene whose product inhibits hypoxia inducible factor 1- (HIF-1)

Prostatic adenocarcinoma often has _____ metastases, which is indicated by lower back pain

Hint: type

_____ syndrome is a combination of: 1. Wilms tumor 2. Early-onset nephrotic syndrome 3. Male pseudohermaphroditism (gonadal dysgenesis)

Metastasis oncogenes such as _____ and TWIST encode transcription factors whose primary function is to promote epithelial-to-mesenchymal transition (EMT).

The cells of _____ tumors contain amine precursor uptake decarboxylase (APUD)

_____ is the microscopic assessment of differentiation in a cancer

Following APC mutation (adenoma-carcinoma sequence), _____ mutations lead to polyp formation (adenoma)

_____ carcinoma is a urinary tract cancer associated with aniline (azo) dyes

_____ is a non-invasive breast cancer characterized by dyscohesive cells due to lack of E-cadherin protein