Neoplasia — Flashcards

Neoplasia is new tissue growth which has three characteristics that distinguish it from hyperplasia and repair:1 - It is _____ 2 - It is irreversible3 - Generally speaking, it is monoclonal*

Benzidine is a carcinogenic aromatic amine found in _____ associated with Transitional Cell Carcinoma of the Bladder

Retinoblastoma is due to mutation in Rb gene located on chromosome _____q14

Gastric carcinoma may spread and involve the _____, also known as a Krukenberg tumor

_____ cancer produces pure osteolytic secondaries.

Hint: System

Transitional cell carcinoma may arise via two distinct pathways: _____ and papillary

_____ is a tumor suppressor gene that encodes p16 which blocks the G1 to S phase of the cell cycle

_____ syndrome is a combination of familial adenomatous polyposis with osteomas and fibromatosis

The T of TNM staging for renal cell carcinoma represents the tumor _____ and involvement of the renal vein

The tumor suppressors encoded by the CDKN2A gene enforce the G1-->S restriction point by:(1) - inhibiting CDK_____/6 (2) - relieving inhibition of P53