Hematopathology — Flashcards

_____ leukemia is defined by the t(9;22) translocation

_____ leukemia may transform into diffuse, large B-cell lymphoma (DLBCL) via the Richter transformation

Hemophilia _____ is a coagulation disorder due to a genetic factor VIII deficiency

_____ is an autosomal dominant hematological disorder that involves spheroid erythrocytes due to a spectrin or ankyrin defect.

_____ consists of malignant "Reed-Sternberg" cells surrounded by inflammatory cells

One subtype of AML is _____, which is characterized by t(15;17)

_____ are identified on blood smear as large RBCs (size) with a bluish (color) cytoplasm

Failure of aggregation with ristocetin assay occurs in _____ disease and Bernard-Soulier syndrome

_____ -blasts are characterized by positive nuclear staining for TdT, which is a DNA polymerase

_____ cells are large B cells with multilobed nuclei and prominent nucleoli ("owl eye" appearance)