Hematopathology — Flashcards

Flashcard 361: What AML subtype is associated with eosinophilia?_____

Answer: AML M4eo (myelomonocytic with eosinophilia)

Flashcard 362: The most common cytogenetic change in multiple myeloma is the deletion of _____

Answer: 13q (or Monosomy 13)

Extra: Deletion of 13q is the most common structural cytogenetic abnormality in Multiple Myeloma, seen in approximately 50% of cases. While translocations involving **14q32** (the IgH locus) are also very common, the most common *deletion* is 13q.

Flashcard 363: _____ is an epigenomic regulatory gene mutated in 90% of follicular lymphomas

Answer: MLL2

Flashcard 364: What is the earliest hematological response to iron therapy in iron-deficiency anemia?_____

Answer: Bone marrow erythroid hyperplasia

Flashcard 365: Blasts usually make up _____% of the circulating cells in accelerated phase of chronic myeloid leukemia

Answer: 10-19

Flashcard 366: In touch preparations of Extranodal NK/T-Cell Lymphoma, large _____philic granules are seen in the cytoplasm of the tumor cells

Answer: azuro

Flashcard 367: Which variant of Reed-Sternberg cells is seen with lymphocyte depleted subtype of Hodgkin's lymphoma?_____

Answer: reticular variant

Flashcard 368: _____ is the most specific marker of Reed Sternberg cell

Answer: PAX5

Flashcard 369: Hematopoetic presentation of acute radiation syndrome is marked by _____

Answer: aplastic anemia

Flashcard 370: _____ lymphadenitis is also known as histiocytic necrotizing lymphadenitis.

Answer: Kikuchi's