Hematopathology — Flashcards

Flashcard 131: Other signs of a leukemoid reaction include _____ peripherally located "dohle bodies" in neutrophils, toxic granulation, and cytoplasmic vacuoles

Answer: basophilic

Flashcard 132: _____ leukemia is a neoplastic proliferation of mature B cells characterized by hairy cytoplasmic processes

Answer: Hairy cell

Flashcard 133: Disseminated intravascular coagulation (DIC) as a paraneoplastic syndrome is most commonly associated with _____ and prostatic adenocarcinoma.

Answer: acute promyelocytic leukemia (APL)

Flashcard 134: CML is distinguished from a leukemoid reaction (benign neutrophilia) by a _____ leukocyte alkaline phosphatase (LAP) stain

Answer: negative

Flashcard 135: Lymphoma is divided into _____ (~85%) and Hodgkin lymphoma (~15%) *bonus: age groups

Answer: non-Hodgkin

Extra: Age groups: - Hodgkin Lymphoma: Bimodal distribution (peaks in young adults ~20s and elderly ~50s+). - Non-Hodgkin Lymphoma: Generally occurs in older adults (incidence increases with age).

Flashcard 136: Endotoxin/Lipopolysaccharide of Gram Negative Bacteria can activate _____, resulting in coagulation and possible DIC (disseminated intravascular coagulation)

Answer: tissue factor

Flashcard 137: Normocytic anemia with _____-vascular hemolysis may cause leakage of hemoglobin into the blood and urine

Answer: intra

Flashcard 138: RBCs stored in _____ can be kept until 21 days

Answer: ACD

Flashcard 139: The _____ subtype of Hodgkin lymphoma typically presents as an enlarging cervical or mediastinal lymph node in a female

Answer: nodular sclerosis

Flashcard 140: _____ is diagnosed via blood smear with a characteristic 'Maltese cross' structure within cells

Answer: Babesiosis