Hematopathology — Flashcards

Aplastic anemia occurs due to damage to _____ stem cells, resulting in pancytopenia (anemia, thrombocytopenia, and leukopenia)

DIC is associated with decreased factors _____ and VIII, which helps distinguish it from vitamin K deficiency

_____ syndrome is a qualitative platelet disorder due to a genetic GPIb deficiency

_____ lymphoma is characterized by a high mitotic index and 'starry-sky' appearance on microscopy

_____ syndromes may be associated with a Pseudo-Pelger-Huet anomaly, which are neutrophils with bilobed nuclei

Left shifts are usually seen with neutrophilia in the acute response to _____ or tissue necrosis

_____ syndrome is characterized by enlarged platelets on blood smear

_____ are pathologic RBCs that have a(n) increased mean corpuscular hemoglobin concentration (MCHC)

Other signs of a leukemoid reaction include _____ peripherally located "dohle bodies" in neutrophils, toxic granulation, and cytoplasmic vacuoles

Hint: color

CML is distinguished from a leukemoid reaction (benign neutrophilia) by a _____ leukocyte alkaline phosphatase (LAP) stain