Dermatopathology — Flashcards

Flashcard 31: _____ of nevus is a change that occurs when nevus cells become non pigmented and resemble neural tissue as they grow deep into the dermis

Answer: Neurotization

Flashcard 32: _____ method is the most specific method for staining melanin and stains it brown black

Answer: Dihydroxyphenylalanine (DOPA)-oxidase

Flashcard 33: Allergic contact dermatitis is a type _____ hypersensitivity reaction

Answer: IV (Delayed-type)

Extra: Irritant contact dermatitis is a non-immunologic reaction caused by direct chemical or physical damage to the skin. In contrast, Allergic contact dermatitis is a Type IV (T-cell mediated) hypersensitivity reaction.

Flashcard 34: Epidermis of an orf lesion shows ballooning degeneration of keratinocytes with eosinophilic _____ inclusions

Answer: cytoplasmic

Flashcard 35: What type of dyskeratosis (benign/neoplastic) is seen in Bowen s disease, squamous cell carcinoma, and actinic keratosis? _____

Answer: Neoplastic

Flashcard 36: _____keratosis is characterized by nuclear pyknosis and condensation of the cytoplasm of keratinocytes.

Answer: Dys

Flashcard 37: Pigmentation in acanthosis nigricans is due to _____

Answer: hyperkeratosis

Flashcard 38: Extramammary Paget's disease of the anus is a rare intraepithelial _____

Answer: adenocarcinoma

Flashcard 39: Melanoma cells have chromatin that is characteristically clumped at the _____ of the nuclear membrane with prominent red (eosinophilic) nucleoli

Answer: periphery

Flashcard 40: _____ is the characteristic feature of histopathological feature of Acute eczema

Answer: Spongiosis