Hair and Nail Disorders — Flashcards

Flashcard 1: _____ may be associated with Munro microabscesses, which are collections of neutrophils in the stratum corneum

Answer: Psoriasis

Flashcard 2: _____ has a characteristic histopathology of "Claw clutching a Ball' appearance

Answer: Lichen nitidus

Flashcard 3: Dermatitis herpetiformis involves the _____ layer of the dermis

Answer: Papillary

Extra: Dermatitis herpetiformis is characterized by subepidermal blisters with microabscesses at the **tips of dermal papillae**. Immunofluorescence shows granular **IgA** deposits.

Flashcard 4: Melanocytic nevi (moles) are common benign neoplasms caused by acquired activating mutations in components of the _____ signaling pathway.

Answer: RAS

Flashcard 5: Homogeneous, _____philic, rounded body resulting from degeneration and death of keratinocytes, is known as Civatte body

Answer: eosino

Flashcard 6: Lichen sclerosus is characterized by _____ of the epidermis and fibrosis (sclerosis) of the dermis

Answer: thinning

Flashcard 7: Elongated dermal papillae usually covered with a single layer of epidermal cells are referred to as _____

Answer: Villi

Flashcard 8: Degeneration of keratinocytes in lichen planus leads to the formation of spaces in the epidermis known as _____

Answer: Max-Joseph Spaces

Flashcard 9: Tiger tail banding of hair follicle seen under polarizing microscopy is diagnostic of _____

Answer: Trichothiodystrophy

Flashcard 10: _____ has a characteristic histopathology of "Claw clutching a Ball' appearance

Answer: Lichen nitidus