Dermatopathology — Flashcards

In **Staphylococcal Scalded-Skin Syndrome** (SSSS), the exfoliative toxin destroys _____ in the stratum granulosum.

Extramammary paget disease of the vulva may be distinguished from melanoma by the following immunohistological features: 1. PAS _____ 2. Keratin + 3. S100 -

Langerhans cells are positive for _____ and S100 on immunohistochemistry

Homogeneous, _____philic, rounded body resulting from degeneration and death of keratinocytes, is known as Civatte body

In regards to wrinkles of aging, there is _____ synthesis of collagen fibrils and increased crosslinking of collagen

Langerhans cells have a single, characteristic folded or grooved nucleus (_____ appearance) with small inconspicuous nucleoli and eosinophilic cytoplasm.

Cylindroma is due to mutation of _____ gene on chromosome 16q12-13

_____ leprosy presents as a spindle-cell proliferation with storiform pattern

Grenz zone is absent in _____ leprosy because the dermal granulomas extend up to the epidermis, thus obstructing the Grenz zone.

_____ of nevus is a change that occurs when nevus cells become non pigmented and resemble neural tissue as they grow deep into the dermis