Cutaneous Manifestations of Systemic Disease — Flashcards

Flashcard 1: Photoallergic contact dermatitis is a type _____ hypersensitivity reaction

Answer: IV

Flashcard 2: Epidermis of an orf lesion shows ballooning degeneration of keratinocytes with eosinophilic _____ inclusions

Answer: cytoplasmic

Flashcard 3: Camel foot appearance is seen in histopathology of _____ psoriasis.

Answer: Plaque-type Note: This refers to the regular elongation and clubbing of rete ridges (also described as 'test tubes in a rack' appearance).

Flashcard 4: Allergic contact dermatitis is a type _____ hypersensitivity reaction

Answer: IV (Delayed-type)

Extra: Irritant contact dermatitis is a non-immunologic reaction caused by direct chemical or physical damage to the skin. In contrast, Allergic contact dermatitis is a Type IV (T-cell mediated) hypersensitivity reaction.

Flashcard 5: _____ microabscess also called as spongiform pustules of Kogoj (deep; usually in the spinous/malpighian layer) are seen in psoriasis

Answer: Neutrophilic

Flashcard 6: Lichen sclerosus is characterized by _____ of the epidermis and fibrosis (sclerosis) of the dermis

Answer: thinning

Flashcard 7: Pigmentation in acanthosis nigricans is due to _____

Answer: hyperkeratosis

Flashcard 8: What type of nevus shows lymphocytic infiltration surrounding nevus cells? _____

Answer: Halo nevus

Flashcard 9: _____ has a characteristic histopathology of "Claw clutching a Ball' appearance

Answer: Lichen nitidus

Flashcard 10: _____ giant cells are lipid-containing macrophages, having a central ring of nuclei while the peripheral cytoplasm is clear due to accumulated lipid

Answer: Touton