Structure and Function of Skin — Flashcards

Flashcard 1: Simple lentigo occurs due to an increase in _____ at dermal-epidermal junction.

Answer: melanocytes

Flashcard 2: Dermatitis herpetiformis involves the _____ layer of the dermis

Answer: Papillary

Extra: Dermatitis herpetiformis is characterized by subepidermal blisters with microabscesses at the **tips of dermal papillae**. Immunofluorescence shows granular **IgA** deposits.

Flashcard 3: _____keratosis is characterized by nuclear pyknosis and condensation of the cytoplasm of keratinocytes.

Answer: Dys

Flashcard 4: Which layer is involved in blister formation in a superficial partial thickness burn?_____

Answer: Papillary dermis

Flashcard 5: _____ is an sweat gland tumor with ductal (apocrine or eccrine) differentiation

Answer: Cylindroma

Flashcard 6: Degeneration of keratinocytes in lichen planus leads to the formation of spaces in the epidermis known as _____

Answer: Max-Joseph Spaces

Flashcard 7: _____ has a characteristic histopathology of "Claw clutching a Ball' appearance

Answer: Lichen nitidus

Flashcard 8: What type of nevus shows lymphocytic infiltration surrounding nevus cells? _____

Answer: Halo nevus

Flashcard 9: _____ giant cells are lipid-containing macrophages, having a central ring of nuclei while the peripheral cytoplasm is clear due to accumulated lipid

Answer: Touton

Flashcard 10: Upward elongation of the dermal papillae, giving an accentuated and sometimes irregular, undulating configuration to the dermal–epidermal junction is known as _____

Answer: papillomatosis