Nucleic Acid Biochemistry — Flashcards

Adenosine is converted to _____ via the enzyme adenosine deaminase (purine salvage)

Vitamins _____ and B12 are necessary for synthesis of DNA precursors

_____ are small, noncoding RNA molecules that post-transcriptionally regulate protein expressiontheir 3' UTR contains sequences determining their specificity

NRTIs inhibit phosphodiester bond formation in a _____ to 5' direction

Pyrimidine synthesis begins with _____, CO2, and 2 ATP

_____ of cytosine makes uracil

dUMP is converted to _____ via the enzyme thymidylate synthase (with methylene THF as a cofactor)

A _____ mutation occurs when there is a deletion or insertion of a number of nucleotides not divisible by 3, resulting in misreading of all nucleotides downstream.

Carbamoyl phosphate synthetase II is regulated by positive feedback via _____ and PRPP

A _____ is negatively charged DNA wrapped around the outside of positively charged proteins called histones