Nucleic Acid Biochemistry — Flashcards

RNA _____ uses dsRNA complementary to an mRNA of interest to "knock down" gene expression

One co-transcriptional modification is the addition of a _____ at the 5' end

The _____ is the site where RNA polymerase II and general transcription factors bind to DNA upstream from a gene locus

Carbamoyl phosphate is combined with _____ to form orotic acid (pyrimidine synthesis)

Guanosine is converted to _____ via the enzyme purine nucleoside phosphorylase (purine salvage)

microRNA often leads to the _____ of target mRNA, thus causing decreased translation into protein

Hypoxanthine is converted to _____ via xanthine oxidase

Which base excision repair enzymes are responsible for filling and sealing the gap from the excised bases?_____ (filling) and DNA ligase III (sealing)

Hint: specific

Xanthine is converted to _____ by xanthine oxidase

Inosine is converted to _____ via the enzyme purine nucleoside phosphorylase (purine salvage)