NEET-PG 2015 Practice Questions

Q: Which of the following statements is true regarding dentigerous cysts?

It arises in relation to unerupted teeth.. ***It arises in relation to unerupted teeth.*** - A **dentigerous cyst** (also known as a follicular cyst) develops from the **reduced enamel epithelium** covering the crown of an un-erupted or impacted tooth. - It is the most common developmental odontogenic cyst and is always associated with the **crown of an impacted tooth**. *It commonly encroaches upon the maxillary antrum.* - While dentigerous cysts can occur with impacted maxillary teeth (like canines), the statement that they **commonly encroach upon the maxillary antrum** is not universally true or a defining characteristic. This is more often seen with cysts of maxillary molars when they are high in the maxilla. - The most common sites are mandibular third molars and maxillary canines, and encroachment on the antrum is not a primary diagnostic feature across all cases. *The mandibular third molar is a common site for occurrence.* - This statement is **true**; the mandibular third molar is indeed the most common tooth associated with dentigerous cysts. However, the question asks for the **most true** statement which is the definition of a dentigerous cyst. - Other common sites include maxillary canines and mandibular premolars. *Dentigerous cysts are more common in the mandible than in the maxilla.* - While the **mandibular third molar** is the most frequently involved tooth, statistically, dentigerous cysts show a roughly **equal distribution** or a slight predilection for the maxilla when all affected teeth are considered (maxillary canines are also very common), making this statement less accurate than the defining characteristic. - The prevalence between the two jaws can vary depending on the study population, but it's not definitively more common in the mandible overall.

Q: Most common precipitant of Raynaud's phenomenon is

Exposure to cold. ***Exposure to cold*** - **Exposure to cold temperatures**, even mild cold, is the most frequent and characteristic trigger for **vasoconstriction** in Raynaud's phenomenon. - This leads to the classic **triphasic color changes** (white, blue, red) in the digits due to restricted blood flow. *Exposure to heat* - **Exposure to heat** generally causes **vasodilation**, which would alleviate rather than precipitate the symptoms of Raynaud's phenomenon. - While sudden temperature changes can sometimes be a factor, direct heat exposure is not a primary recognized trigger. *Psychosocial triggers* - **Emotional stress** and anxiety can indeed precipitate Raynaud's episodes in some individuals, as the **sympathetic nervous system** plays a role in vasoconstriction. - However, **cold exposure** remains the most common and potent precipitating factor across the majority of cases. *Exertion* - **Physical exertion** typically leads to **vasodilation** in working muscles and increased blood flow to the skin for heat dissipation. - It is not a common or direct precipitant of the localized vasoconstrictive attacks seen in Raynaud's phenomenon.

Q: What is the main contraindication for performing a liver biopsy?

Severe coagulopathy. ***Severe coagulopathy*** - **Severe coagulopathy** is the main contraindication for liver biopsy due to a significantly increased risk of **hemorrhage** [1]. - A **prothrombin time (PT)** or **activated partial thromboplastin time (aPTT)** significantly prolonged beyond the normal range, or an **INR > 1.5**, should be corrected before the procedure [1]. *Severe thrombocytopenia* - While **thrombocytopenia** (platelet count <50,000/µL) does increase bleeding risk, it is often correctable with a **platelet transfusion** prior to biopsy, making it a relative rather than an absolute contraindication [1]. - The risk of major bleeding is typically lower with isolated thrombocytopenia compared to severe coagulopathy. *Liver hemangioma* - The presence of a **liver hemangioma** at the biopsy site is a contraindication as biopsying it can lead to massive hemorrhage. - However, if the biopsy can be performed safely away from the hemangioma, it is not an absolute contraindication to the procedure itself. *Presence of ascites* - **Ascites** can complicate a liver biopsy by increasing the risk of **peritoneal bleeding** and difficulty in targeting the liver [1]. - However, it is often manageable by draining the ascites or using imaging guidance, making it a relative contraindication rather than an absolute one [1].

Q: A patient presents with difficulty with swallowing liquids but not solids. The best investigation to make a diagnosis is

Manometry. ***Manometry*** - **Esophageal manometry** measures the pressure and coordination of muscle contractions in the esophagus, which is crucial for diagnosing motility disorders like **achalasia** [1] or **esophageal spasm** [2] that can cause difficulty swallowing liquids. - The symptom of difficulty swallowing liquids but not solids (**paradoxical dysphagia**) is characteristic of a primary esophageal motility disorder rather than a structural obstruction [1]. *Endoscopy* - **Endoscopy** is primarily used to visualize the esophagus and stomach for structural abnormalities such as **strictures**, **tumors**, or **inflammation** [1]. - While it can rule out structural causes, it is less effective for diagnosing purely functional or motility disorders [1]. *Endoscopic ultrasound* - **Endoscopic ultrasound (EUS)** provides detailed imaging of the esophageal wall and surrounding structures, helping to stage cancers or identify extrinsic compression. - It is not the primary investigation for assessing **esophageal motility**. *PET CT* - **PET CT** is primarily used in oncology for **cancer staging**, recurrence detection, and assessing metabolic activity of lesions. - It has limited utility in the initial diagnosis of a **swallowing disorder**, especially one indicating a motility issue.

Q: Which of the following is true about menetrier's disease

There is decreased gastric acid secretion. ***It is a premalignant condition*** - Menetrier's disease is characterized by **hyperplastic gastric mucosa** and is considered a **premalignant condition** due to its association with gastric cancers. - Regular surveillance and monitoring are recommended because of this increased risk for malignancy. *Affects the stomach and small intestines* - Menetrier's disease primarily **affects the stomach**, specifically leading to excessive growth of the gastric mucosa. - It does not typically involve the **small intestines**, which differentiates it from other gastrointestinal diseases. *There is increased gastric acid secretion* - In Menetrier's disease, there is actually a **decreased gastric acid secretion** due to the alteration of gastric mucosal structure. - This condition leads to **hypochlorhydria**, contrasting with conditions that increase acid secretion like Zollinger-Ellison syndrome. *Atrophied mucosal folds are seen* - Menetrier's disease is marked by **hypertrophy of the gastric folds**, not atrophy, resulting in **enlarged rugae** within the stomach. - Atrophied mucosal folds are more associated with conditions like chronic atrophic gastritis.

Q: Which of the following is NOT a principle of negative pressure wound therapy?

Clearance of infection. ***Clearance of infection*** - While negative pressure wound therapy (NPWT) can help manage heavily colonized wounds by removing exudate and reducing bacterial burden, it is **not a primary treatment for active infection**. - **Systemic antibiotics** or local antiseptics are required to truly clear an infection, as NPWT alone cannot eliminate deep-seated pathogens. *Stabilization of wound environment* - NPWT helps to **stabilize the wound bed** by holding it in place, protecting it from external contamination and mechanical stress. - This creates an optimal environment for **wound healing** by preventing disruption of newly formed granulation tissue. *Macrodeformation of the wound* - The negative pressure applied to the wound surface causes the wound edges to be drawn together, leading to **macrodeformation**. - This effect reduces wound size and promotes **epithelialization** and **wound contraction**. *Decreased edema* - NPWT actively removes **excess interstitial fluid** and exudate from the wound bed, leading to a significant reduction in edema. - This reduction in swelling improves **perfusion** to the wound tissues and promotes better healing.

Q: Where does spontaneous esophageal rupture (Boerhaave syndrome) most commonly occur?

Above the diaphragmatic aperture. ***Above the diaphragmatic aperture*** - Boerhaave syndrome, or spontaneous esophageal rupture, most commonly occurs in the **distal esophagus**, just above the diaphragmatic aperture. - This region is particularly susceptible due to increased **intraluminal pressure** during forceful vomiting, combined with a lack of muscular support and a thinner esophageal wall. - The rupture typically occurs in the **left posterolateral wall** of the lower third of the esophagus, approximately **2-5 cm above the gastroesophageal junction**. *Below the diaphragmatic aperture* - Ruptures below the diaphragmatic aperture are less common in Boerhaave syndrome, as the **lower esophageal sphincter** and surrounding diaphragmatic crura provide more support. - While other forms of esophageal injury can occur here, a spontaneous rupture due to vomiting is less typical in this location. *Pharyngoesophageal junction* - Ruptures at the pharyngoesophageal junction are known as **Zenker's diverticulum ruptures** or other types of perforation, typically not Boerhaave syndrome. - This area is prone to tears from instrumentation or foreign bodies but not usually from the extreme pressure of forceful vomiting (which affects the distal esophagus more). *At the crossing of the arch of aorta* - The mid-esophagus at the level of the aortic arch is not a common site for Boerhaave syndrome. - Although the esophagus is constricted here, the primary stress during forceful vomiting is concentrated in the **distal esophagus**.

Q: What is the treatment of choice in desmoid tumors?

Wide excision. ***Wide excision*** - For **desmoid tumors**, **complete surgical resection with clear margins** is the primary treatment of choice due to their infiltrative nature and high recurrence rates. - This approach aims to minimize local recurrence and prevent tumor progression, which can impact adjacent structures. *Irradiation* - **Radiation therapy** is typically reserved as an **adjuvant** treatment after surgery or for unresectable tumors, not as a primary standalone treatment. - While it can help reduce recurrence rates, it carries risks of **secondary malignancies** and local tissue damage. *Local excision* - **Local excision** alone is insufficient for desmoid tumors due to their **infiltrative growth pattern** and high propensity for **local recurrence** if positive margins remain. - It often leads to incomplete removal, necessitating further intervention and increasing the risk of tumor progression. *Local excision following radiation* - Combining local excision with initial radiation is not the preferred sequence; **wide surgical excision** is typically performed first. - Radiation might be considered preoperatively in specific cases to **reduce tumor size** or postoperatively for **positive margins**, but starting with local excision after initial radiation is not the standard primary management.

Q: Which of the following is resected in Whipple's operation, except?

Neck of pancreas. ***Neck of pancreas*** - In a **Whipple procedure** (pancreaticoduodenectomy), the **neck of the pancreas** is the site of transection (division), not resection. - The pancreas is divided at the neck, and the remaining **body and tail** are preserved and anastomosed to the jejunum for pancreatic drainage. *Duodenum* - The **entire duodenum** is resected during a Whipple operation as it shares intimate anatomical relations with the pancreatic head. - Complete duodenal removal is necessary to achieve adequate **oncological margins** and remove all associated lymphatic drainage. *Head of pancreas* - The **head of the pancreas** is the primary structure resected in a Whipple procedure. - This resection is typically performed for **pancreatic adenocarcinoma** or **periampullary tumors** requiring en bloc removal. *Common bile duct* - The **distal common bile duct** is resected as part of the specimen to ensure complete tumor excision. - The remaining **proximal bile duct** is reconstructed via **hepaticojejunostomy** to restore biliary drainage.

Q: CA Breast may locally spread to all of the following muscles except

Latissimus Dorsi. ***Latissimus Dorsi*** - The **latissimus dorsi** muscle is located on the posterior aspect of the trunk and arm, significantly deeper and further away from the breast tissue compared to other surrounding muscles. - Direct local invasion of breast cancer to the latissimus dorsi is rare and typically requires extensive tumor growth or metastasis to more distant sites before affecting this muscle. *Pectoralis Minor* - The **pectoralis minor** muscle lies directly beneath the pectoralis major and is in close proximity to the deeper aspects of the breast tissue. - Tumors that invade the **deep fascia** of the breast can directly extend into this muscle. *Serratus Anterior* - The **serratus anterior** muscle is located on the lateral wall of the thorax, forming part of the chest wall beneath the breast. - **Aggressive breast cancers**, particularly those in the outer quadrants, can invade the fascial planes covering this muscle. *Pectoralis Major* - The **pectoralis major** forms the anterior wall of the axilla and lies directly beneath the majority of the breast tissue. - It is one of the most common muscles to be affected by **direct local invasion** from breast cancer due to its anatomical proximity.

Question 1

Which of the following statements is true regarding dentigerous cysts?

Accepted Answer

It arises in relation to unerupted teeth.

Answer

It commonly encroaches upon the maxillary antrum.

Answer

The mandibular third molar is a common site for occurrence.

Answer

Dentigerous cysts are more common in the mandible than in the maxilla.

Question 2

Most common precipitant of Raynaud's phenomenon is

Accepted Answer

Exposure to cold

Answer

Exposure to heat

Answer

Psychosocial triggers

Answer

Exertion

Question 3

What is the main contraindication for performing a liver biopsy?

Accepted Answer

Severe coagulopathy

Answer

Severe thrombocytopenia

Answer

Liver hemangioma

Answer

Presence of ascites

Question 4

A patient presents with difficulty with swallowing liquids but not solids. The best investigation to make a diagnosis is

Accepted Answer

Manometry

Answer

Endoscopy

Answer

Endoscopic ultrasound

Answer

PET CT

Question 5

Which of the following is true about menetrier's disease

Accepted Answer

There is decreased gastric acid secretion

Answer

Atrophied mucosal folds are seen

Answer

It is premalignant condition

Answer

It causes increased gastric acid secretion

Question 6

Which of the following is NOT a principle of negative pressure wound therapy?

Accepted Answer

Clearance of infection

Answer

Macrodeformation of the wound

Answer

Decreased edema

Answer

Stabilization of wound environment

Question 7

Where does spontaneous esophageal rupture (Boerhaave syndrome) most commonly occur?

Accepted Answer

Above the diaphragmatic aperture

Answer

Below the diaphragmatic aperture

Answer

Pharyngoesophageal junction

Answer

At the crossing of the arch of aorta

Question 8

What is the treatment of choice in desmoid tumors?

Accepted Answer

Wide excision

Answer

Irradiation

Answer

Local excision

Answer

Local excision following radiation

Question 9

Which of the following is resected in Whipple's operation, except?

Accepted Answer

Neck of pancreas

Answer

Duodenum

Answer

Head of pancreas

Answer

Common bile duct

Question 10

CA Breast may locally spread to all of the following muscles except

Accepted Answer

Latissimus Dorsi

Answer

Pectoralis Minor

Answer

Serratus Anterior

Answer

Pectoralis Major

NEET-PG 2015

Dental

Internal Medicine

Pathology

Surgery