NEET-PG 2015 Practice Questions

Q: Locking of the knee involves which of the following?

Internal rotation of the femur with the foot on the ground. ***Internal rotation of the femur with the foot on the ground*** - When the foot is on the ground (closed kinematic chain), the **femur rotates internally on the tibia** during the end stages of knee extension. This creates a more stable, "locked" position of the knee. - This **terminal rotation of the femur** increases the contact area and tension in the cruciate ligaments, enhancing joint stability for weight-bearing. *Internal rotation of the tibia with the foot on the ground* - This describes the action of the **popliteus muscle** when "unlocking" the knee from full extension, not the locking mechanism itself. - With the foot on the ground, the tibia is fixed, and internal rotation would typically be a movement for unlocking, not locking. *Contraction of the popliteus muscle* - The **popliteus muscle** is primarily responsible for **unlocking the knee** from full extension, by causing internal rotation of the tibia (or external rotation of the femur). - Its contraction would lead to initial flexion of the knee, releasing the locked position, not establishing it. *External rotation of femur with the foot off the ground* - With the foot off the ground (open kinematic chain), **external rotation of the tibia** occurs during the final degrees of extension to lock the knee, not external rotation of the femur. - The locking mechanism requires specific relative rotation between femur and tibia; external rotation of the femur alone would not achieve the screw-home mechanism necessary for knee locking.

Q: Number of stem villi at term in human placenta is?

240. ***240*** - At term, the **human placenta** contains numerous **stem villi** which branch extensively to form the villous tree. - The approximate number of **stem villi** at term is around **240**, contributing to the large surface area for maternal-fetal exchange. *60* - This number is significantly **lower** than the actual count of **stem villi** found in a mature, term placenta. - Such a low number would result in an **insufficient surface area** for effective nutrient and gas exchange. *120* - While higher than 60, this number is still **underestimated** for the quantity of **stem villi** present in a full-term human placenta. - A placenta with only 120 stem villi might not be able to adequately support a fetus at term. *480* - This number is an **overestimation** of the typical count of **stem villi** in a human placenta at term. - While villi are extensive, 480 stem villi represent a significantly higher number than usually observed.

Q: Which of the following metal ions is associated with secondary Parkinsonisms?

Manganese (Mn). ***Manganese (Mn)*** - Chronic exposure to high levels of **manganese** can lead to **manganism**, a neurological disorder characterized by **Parkinsonian-like symptoms**, including bradykinesia, rigidity, and gait disturbances [1]. - This is due to manganese accumulation in the **basal ganglia**, particularly the **globus pallidus**, affecting dopaminergic pathways. *Magnesium (Mg)* - **Magnesium** is an essential mineral vital for numerous bodily functions, including nerve and muscle function. - While imbalances can cause neurological issues (e.g., tremors with hypomagnesemia), it is not directly associated with **secondary parkinsonism**. *Selenium (Se)* - **Selenium** is a trace element with antioxidant properties, important for thyroid hormone metabolism and immune function. - Both deficiency and toxicity can cause various health problems, but it is not known to cause **secondary parkinsonism**. *Molybdenum (Mo)* - **Molybdenum** is an essential trace element that functions as a cofactor for several enzymes. - No known association exists between molybdenum exposure, deficiency, or toxicity and the development of **secondary parkinsonism**.

Q: Which of the following is not considered a marker of ovarian reserve?

Inhibin A. ***Inhibin A*** - **Inhibin A** levels primarily rise during the mid to late luteal phase and are involved in regulating FSH, but they are not a reliable or commonly used marker for **ovarian reserve**. - Its fluctuations are more indicative of the presence of a **corpus luteum** and short-term ovarian function rather than the total follicular pool. *Inhibin B* - **Inhibin B** is produced by granulosa cells of small antral follicles and is an important marker of **ovarian reserve**. - It inversely correlates with **FSH** levels in the early follicular phase, reflecting the number of developing follicles. *Ovarian volume* - **Ovarian volume**, particularly when measured by ultrasound, can be an indicator of **ovarian reserve**. - Smaller ovarian volume is generally associated with a reduced number of **antral follicles** and lower ovarian reserve. *Anti-Müllerian Hormone (AMH)* - **AMH** is a well-established and highly reliable marker of **ovarian reserve**, produced by the granulosa cells of preantral and small antral follicles. - Its levels correlate directly with the total number of remaining **primordial follicles** and are relatively stable throughout the menstrual cycle.

Q: Most common site of hypertensive intraparenchymal hemorrhage in the brain?

Putamen. ***Putamen*** - The **putamen** is the most frequent site for **hypertensive intraparenchymal hemorrhages** [1] due to the presence of numerous small, thin-walled arterioles (lenticulostriate arteries) that are highly susceptible to damage from chronic hypertension [1]. - Hemorrhages in this region often cause **contralateral hemiparesis**, **hemianesthesia**, and **gaze deviation** towards the side of the lesion due to involvement of nearby motor and sensory pathways [1]. *Thalamus* - While the **thalamus** is a common site for hypertensive hemorrhages, it is less common than the putamen [1], [2]. - Thalamic hemorrhages typically cause **contralateral sensory loss**, **oculomotor dysfunction**, and sometimes **aphasia** if the dominant hemisphere is affected. *Cerebellum* - **Cerebellar hemorrhages** are less frequent than those in the basal ganglia or thalamus [1]. - Symptoms usually include **ataxia**, **nystagmus**, vomiting, and potential brainstem compression if large. *Pons* - **Pontine hemorrhages** are among the most severe and are often rapidly fatal due to damage to vital brainstem structures [1], [2]. - They typically present with **coma**, **quadriparesis**, **pinpoint pupils**, and rapid progression to respiratory arrest.

Q: Which of the following drugs is most commonly used for cardiovascular support in post-resuscitation care of neonates?

Dopamine. ***Dopamine*** - **Dopamine** is often the first-line vasopressor used in neonates for **hypotension** unresponsive to fluid resuscitation, especially in the context of post-resuscitation care, due to its dose-dependent effects on cardiac output and systemic vascular resistance. - It increases **cardiac contractility** and **heart rate** at moderate doses (beta-1 adrenergic effects) and can improve renal blood flow at lower doses. *Sodium Bicarbonate* - **Sodium bicarbonate** is used to correct severe metabolic acidosis but is generally not recommended in the initial stages of neonatal resuscitation or for routine cardiovascular support due to potential adverse effects like rebound acidosis and hypernatremia. - Its use is typically reserved for documented severe metabolic acidosis after adequate ventilation and circulation have been established. *Epinephrine* - **Epinephrine** is primarily used during active cardiorespiratory arrest for its potent vasoconstrictive and inotropic effects, and for sustained **bradycardia** unresponsive to ventilation and chest compressions. - While it has strong cardiovascular effects, it is not the most common drug for *post-resuscitation cardiovascular support* unless there is persistent shock or bradycardia despite dopamine. *Dobutamine* - **Dobutamine** is an inotropic agent primarily used to improve myocardial contractility and cardiac output with less chronotropic effect than dopamine, making it beneficial in conditions with low cardiac output and normal blood pressure. - It is less commonly used as an initial agent for post-resuscitation **hypotension** in neonates compared to dopamine, which also offers systemic vasoconstriction to raise blood pressure.

Q: Which of the following statements about encephalocoele is false?

Common in the parietal region. ***Common in the parietal region*** - This statement is **false** because encephaloceles are **rarely found in the parietal region** (only 10-15% of cases). - **Occipital encephaloceles** are most common in Western populations (75-80%), while **frontal/sincipital encephaloceles** are most common in Southeast Asia including India (40-60%). - **Parietal encephaloceles** represent only a small minority of cases globally, making this statement incorrect. *It is a neural tube defect* - **Encephalocele** is indeed a type of **neural tube defect (NTD)**, resulting from incomplete closure of the neural tube during embryonic development. - Specifically, it involves a defect in the skull that allows for protrusion of brain tissue and/or meninges. *Can be associated with hydrocephalus* - **Hydrocephalus**, or the accumulation of cerebrospinal fluid in the brain, is a known complication and associated condition with encephaloceles. - The abnormal brain development and structural defects can disrupt normal CSF flow and absorption, particularly with posterior encephaloceles. *It is protrusion of neural tissue through a defect* - This is the defining characteristic of an **encephalocele**: the **herniation of intracranial contents**, such as brain tissue, meninges, or both, through a congenital **bony defect** in the skull. - The contents of the sac can vary (meninges only = meningocele; brain tissue included = meningoencephalocele), influencing clinical presentation and prognosis.

Q: In which of the following surgeries is monopolar cautery preferred over bipolar cautery?

Surgery of the Hip. ***Surgery of the Hip*** - **Monopolar cautery** is preferred in surgeries like hip surgery where a larger area needs to be coagulated, as it provides a wider field of effect and can be more efficient for **deep tissue coagulation**. - Its mechanism relies on the current passing through the patient to a large **dispersive electrode (grounding pad)**, making it suitable for extensive tissue work. *Hand Surgery* - In **hand surgery**, delicate structures like nerves and tendons are abundant, making **bipolar cautery** safer due to its localized current flow and reduced risk of inadvertent thermal spread. - **Bipolar cautery** limits the current to a small area between the two prongs of the instrument, thus minimizing damage to surrounding tissues. *Surgery around Penis* - **Bipolar cautery** is generally preferred in sensitive areas like the penis, due to its localized effect and reduced risk of thermal injury to adjacent delicate structures. - The avoidance of current passing through the body to a grounding pad in **bipolar modality** is especially important in areas with potential for nerve damage or scarring. *Surgery around the face* - Surgically around the face often involves delicate tissues and structures where **bipolar cautery** is favored to prevent widespread thermal damage and minimize scarring or nerve injury. - The confined current path of **bipolar cautery** makes it ideal for precision work in cosmetic or reconstructive facial surgery.

Q: All of the following are true about Nissen Fundoplication except which of the following?

Reinforcement is done only in the posterior half. ***Reinforcement is done only in the posterior half*** - This statement is incorrect because the **Nissen fundoplication** typically involves a **360-degree wrap** of the gastric fundus around the lower esophagus. - A 360-degree wrap provides complete reinforcement to prevent reflux, unlike a partial wrap which might be used in other procedures but not a standard Nissen. *It is done for GERD* - **Nissen fundoplication** is a common surgical procedure performed to treat severe **Gastroesophageal Reflux Disease (GERD)** that is refractory to medical management. - The procedure aims to strengthen the **lower esophageal sphincter (LES)** and prevent the reflux of stomach contents into the esophagus. *Upper part of stomach is plicated around the lower esophagus* - Specifically, the **fundus** (upper part) of the stomach is wrapped around the distal esophagus to create a functional valve. - This wrap helps to reinforce the LES and prevent stomach acid from flowing back up into the esophagus. *It is done for paraesophageal hiatus hernia* - **Nissen fundoplication** is often performed concurrently with the repair of a **hiatal hernia**, especially a **paraesophageal hernia**, to anchor the stomach in its correct anatomical position and prevent recurrence. - Repair of the hernia alone may not be sufficient to prevent reflux, making the fundoplication an important additional step.

Question 1

Locking of the knee involves which of the following?

Accepted Answer

Internal rotation of the femur with the foot on the ground

Answer

Internal rotation of the tibia with the foot on the ground

Answer

Contraction of the popliteus muscle

Answer

External rotation of femur with the foot off the ground

Question 2

Number of stem villi at term in human placenta is?

Accepted Answer

240

Answer

60

Answer

120

Answer

480

Question 3

Which of the following metal ions is associated with secondary Parkinsonisms?

Accepted Answer

Manganese (Mn)

Answer

Magnesium (Mg)

Answer

Selenium (Se)

Answer

Molybdenum (Mo)

Question 4

What is the most appropriate management for a 28-year-old hemodynamically stable patient with mild abdominal pain and an unruptured tubal ectopic pregnancy measuring 2.5 x 3 cm, with β-hCG level of 8500 mIU/mL, visible fetal cardiac activity, and who desires future fertility?

Accepted Answer

Laparoscopic salpingostomy

Answer

Methotrexate therapy

Answer

Laparoscopic salpingectomy

Answer

Expectant management

Question 5

Which of the following is not considered a marker of ovarian reserve?

Accepted Answer

Inhibin A

Answer

Ovarian volume

Answer

Inhibin B

Answer

Anti-Müllerian Hormone (AMH)

Question 6

Most common site of hypertensive intraparenchymal hemorrhage in the brain?

Accepted Answer

Putamen

Answer

Thalamus

Answer

Cerebellum

Answer

Pons

Question 7

Which of the following drugs is most commonly used for cardiovascular support in post-resuscitation care of neonates?

Accepted Answer

Dopamine

Answer

Dobutamine

Answer

Epinephrine

Answer

Sodium Bicarbonate

Question 8

Which of the following statements about encephalocoele is false?

Accepted Answer

Common in the parietal region

Answer

It is a neural tube defect

Answer

Can be associated with hydrocephalus

Answer

It is protrusion of neural tissue through a defect

Question 9

In which of the following surgeries is monopolar cautery preferred over bipolar cautery?

Accepted Answer

Surgery of the Hip

Answer

Surgery around Penis

Answer

Hand Surgery

Answer

Surgery around the face

Question 10

All of the following are true about Nissen Fundoplication except which of the following?

Accepted Answer

Reinforcement is done only in the posterior half

Answer

It is done for GERD

Answer

Upper part of stomach is plicated around the lower esophagus

Answer

It is done for paraesophageal hiatus hernia

NEET-PG 2015

Anatomy

Internal Medicine

Obstetrics and Gynecology

Pathology

Pediatrics

Surgery