Anatomy
1 questionsCrural index is:
NEET-PG 2012 - Anatomy NEET-PG Practice Questions and MCQs
Question 691: Crural index is:
- A. Length of tibia/femur x 100 (Correct Answer)
- B. Length of radius/humerus x 100
- C. Length of fibula/tibia x 100
- D. Length of radius/ulna x 100
Explanation: ***Length of tibia/femur x 100*** - The **crural index** is a measure used in physical anthropology and comparative anatomy to describe the proportion of the lower leg to the thigh. - It is calculated by dividing the **length of the tibia** (lower leg bone) by the **length of the femur** (thigh bone) and multiplying by 100 to express it as a percentage. *Length of radius/humerus x 100* - This formula describes the **brachial index**, which measures the proportion of the forearm to the upper arm. - It does not represent the crural index, which refers specifically to the **lower limb**. *Length of fibula/tibia x 100* - This ratio compares the two bones within the lower leg but is not the definition of the **crural index**. - The crural index focuses on the relative length of the lower leg to the entire thigh, reflecting overall **limb proportions**. *Length of radius/ulna x 100* - This ratio compares the lengths of the two bones in the forearm and does not correspond to the **crural index**. - The crural index involves the **tibia** and **femur**, which are bones of the lower limb.
Biochemistry
1 questionsWhat vitamin is significantly absent in breast milk?
NEET-PG 2012 - Biochemistry NEET-PG Practice Questions and MCQs
Question 691: What vitamin is significantly absent in breast milk?
- A. Vitamin D
- B. Vitamin K (Correct Answer)
- C. Vitamin C
- D. Vitamin A
Explanation: ***Vitamin K*** - Breast milk contains **critically low amounts** of **vitamin K** (approximately 2-5 μg/L), making it the **most significantly absent** vitamin in breast milk. - Newborns are at high risk for **Vitamin K deficiency bleeding (VKDB)**, which can be life-threatening. - This deficiency is so critical that **prophylactic vitamin K injection** is routinely administered to **all newborns** at birth to prevent hemorrhagic disease. - Vitamin K is essential for the synthesis of **clotting factors II, VII, IX, and X** in the liver. *Vitamin D* - While breast milk does contain **some vitamin D**, the levels are often **insufficient** to meet the infant's daily requirements (contains ~25-78 IU/L; infant needs 400 IU/day). - However, it is **present in measurable amounts**, unlike vitamin K which is nearly absent. - Infants are recommended to receive **vitamin D supplementation** starting soon after birth, especially if the mother has low vitamin D levels or limited **sun exposure**. *Vitamin C* - **Breast milk** contains adequate amounts of **vitamin C** (40-50 mg/L), which is sufficient for the infant's needs. - Maternal diet typically provides enough vitamin C to ensure its presence in breast milk. *Vitamin A* - Breast milk is a **good source** of **vitamin A**, particularly in the form of **beta-carotene** and retinol. - Vitamin A levels in breast milk are adequate for infant **vision development** and **immune function**.
Community Medicine
1 questionsSchistosomiasis is an example of which type of zoonosis that requires an intermediate host?
NEET-PG 2012 - Community Medicine NEET-PG Practice Questions and MCQs
Question 691: Schistosomiasis is an example of which type of zoonosis that requires an intermediate host?
- A. Meta-zoonoses (Correct Answer)
- B. Cyclo-zoonoses
- C. Direct-zoonoses
- D. Sporo-zoonoses
Explanation: ***Meta-zoonoses*** - **Meta-zoonoses** are defined as zoonotic diseases that require an **intermediate invertebrate host** for the completion of the parasite's life cycle. - **Schistosomiasis** fits this definition as it involves fresh water snails acting as an intermediate host, where the parasite undergoes essential developmental stages. *Cyclo-zoonoses* - **Cyclo-zoonoses** require **more than one vertebrate host species** but no invertebrate host for the completion of the infectious agent's life cycle. - An example would be **Taeniasis**, which involves humans and cattle or pigs, but not an invertebrate. *Direct-zoonoses* - **Direct-zoonoses** are transmitted directly from an **infected vertebrate host to a susceptible vertebrate host** without the need for an intermediate host or vector. - Examples include **rabies** or **brucellosis**, which are passed directly from animals to humans. *Sporo-zoonoses* - **Sporo-zoonoses** are zoonoses where the infectious agent undergoes **sporogonic development in an invertebrate host**, but this term is not a standard or widely recognized category in the same way as direct, cyclo-, or meta-zoonoses. - The more appropriate term for diseases involving an invertebrate intermediate host is **meta-zoonoses**.
Forensic Medicine
2 questionsGastric lavage is contraindicated in which of the following?
La facies sympathique is seen in ?
NEET-PG 2012 - Forensic Medicine NEET-PG Practice Questions and MCQs
Question 691: Gastric lavage is contraindicated in which of the following?
- A. Organophosphorus Poisoning
- B. Dhatura poisoning
- C. Arsenic poisoning
- D. Kerosene poisoning (Correct Answer)
Explanation: ***Kerosene poisoning*** - Gastric lavage is contraindicated in **kerosene poisoning** due to the high risk of **aspiration pneumonitis**. - Kerosene is a **hydrocarbon**, and aspiration of even small amounts can cause severe lung damage. *Arsenic poisoning* - **Gastric lavage** can be performed in arsenic poisoning, especially if the ingestion occurred recently, to remove unabsorbed toxin. - Activated charcoal is less effective for arsenic, making lavage a more relevant intervention in acute settings. *Organophosphorus Poisoning* - Gastric lavage is generally recommended within an hour of ingestion for **organophosphorus poisoning** to remove the toxic substance. - This helps reduce systemic absorption and mitigate the severe **cholinergic crisis** caused by these agents. *Dhatura poisoning* - **Gastric lavage** is indicated in dhatura poisoning, particularly if presenting within a few hours of ingestion, to remove unabsorbed **atropine-like alkaloids**. - This helps in reducing the **anticholinergic effects** and improving patient outcomes.
Question 692: La facies sympathique is seen in ?
- A. Hanging (Correct Answer)
- B. Strangulation
- C. Myocardial insufficiency
- D. Railway accident
Explanation: ***Hanging*** - **La facies sympathique** is a term used to describe the facial appearance in cases of **hanging**, characterized by a serene or peaceful look often associated with venous congestion rather than extreme distress. - This appearance is due to the obstruction of venous return from the head while arterial supply continues for a short period, leading to a relatively natural facial expression. *Strangulation* - **Strangulation** typically results in a more dramatic and distressed facial appearance, often with prominent signs of struggle, petechial hemorrhages, and cyanosis. - The compression of both arteries and veins, along with the trachea, leads to rapid and severe cerebral anoxia and overt signs of asphyxia. *Myocardial insufficiency* - **Myocardial insufficiency** (heart failure) usually presents with signs of impaired circulation, such as pallor, cyanosis (especially acrocyanosis), edema, and shortness of breath, but not a specific "sympathetic facies." - The facial expression would more likely reflect distress from dyspnea or discomfort rather than a serene appearance. *Railway accident* - Fatalities from **railway accidents** typically involve severe trauma, disfigurement, and extensive injuries to the head and body. - The facial appearance in such cases would be consistent with massive blunt force trauma, lacerations, or crush injuries, which are inconsistent with "la facies sympathique."
Microbiology
4 questionsWhich organism can be isolated from stool & sputum?
Largest intestinal protozoan is?
Which poxvirus does not grow in eggs or animal cells?
Which virus is primarily responsible for causing Ebola virus disease, a type of hemorrhagic fever?
NEET-PG 2012 - Microbiology NEET-PG Practice Questions and MCQs
Question 691: Which organism can be isolated from stool & sputum?
- A. Fasciola
- B. P. carinii
- C. Clonorchis
- D. Paragonimus (Correct Answer)
Explanation: ***Paragonimus*** - *Paragonimus* species, particularly *P. westermani* (the **lung fluke**), are known to infest the lungs, leading to symptoms like **cough** and **sputum production**, where their eggs can be found. - While residing in the lungs, eggs can be swallowed, passed through the gastrointestinal tract, and subsequently found in **stool samples**. *Fasciola* - *Fasciola hepatica* (the **sheep liver fluke**) primarily infects the **liver and biliary ducts**. - Its eggs are typically found in **stool samples** but not in sputum, as it does not infest the respiratory tract. *Clonorchis* - *Clonorchis sinensis* (the **Chinese liver fluke**) also primarily inhabits the **bile ducts** of the liver. - Similar to *Fasciola*, its eggs are excreted in **feces** and are not found in sputum. *P. carinii* - *Pneumocystis jirovecii* (formerly *Pneumocystis carinii*) is a **fungus** that causes **pneumonia** (PCP) in immunocompromised individuals. - It is exclusively found in the **lungs** and identified in respiratory specimens like sputum or bronchoalveolar lavage, not in stool.
Question 692: Largest intestinal protozoan is?
- A. E. coli
- B. Balantidium coli (Correct Answer)
- C. Giardia
- D. T. gondii
Explanation: ***Balantidium coli*** - *Balantidium coli* is the **largest protozoan parasite** known to infect humans, specifically found in the intestines. - It causes **balantidiasis**, an intestinal infection, and is notable for its ciliated trophozoite stage. *E. coli* - *E. coli* is a **bacterium**, not a protozoan. - While it is a common inhabitant of the intestines, it is significantly smaller than parasitic protozoa. *Giardia* - *Giardia lamblia* (or *intestinalis*) is a **flagellate protozoan** that causes giardiasis. - Though an intestinal parasite, it is considerably smaller than *Balantidium coli*. *T. gondii* - *Toxoplasma gondii* is an **intracellular protozoan parasite** known for causing toxoplasmosis. - It is much smaller than *Balantidium coli* and primarily infects cells, not existing as a large free-living form in the intestine.
Question 693: Which poxvirus does not grow in eggs or animal cells?
- A. Cow pox
- B. Vaccinia
- C. Variola
- D. Molluscum contagiosum (Correct Answer)
Explanation: ***Molluscum contagiosum*** - This poxvirus is unique among human poxviruses as it **cannot be propagated in cell culture** or embryonated eggs. - It specifically replicates in **human epidermal cells**, causing characteristic skin lesions. *Cow pox* - Cowpox virus can be readily grown in **cell cultures** (e.g., Vero cells) and in **embryonated eggs**, where it produces pocks on the chorioallantoic membrane (CAM). - It is known for its ability to **infect a wide range of host cells and animals**. *Vaccinia* - Vaccinia virus is a widely studied poxvirus that grows efficiently in various **mammalian cell lines** (e.g., Hela, Vero cells) and on the **chorioallantoic membrane of embryonated eggs**. - Its broad host range and ease of culture make it a popular **viral vector** for research and vaccine development. *Variola* - Variola virus, the causative agent of smallpox, was successfully propagated in **cell cultures** (e.g., primary human embryonic kidney cells) and in **embryonated chicken eggs**, producing characteristic pock lesions. - Its ability to grow in these systems was crucial for **vaccine production** and research before its eradication.
Question 694: Which virus is primarily responsible for causing Ebola virus disease, a type of hemorrhagic fever?
- A. Ebola virus (Correct Answer)
- B. Phlebovirus
- C. West Nile virus
- D. None of the options
Explanation: ***Ebola virus*** - The disease is named after the **Ebola River** in Congo, where it was first identified. - The **Ebola virus** is a member of the **Filoviridae family**, known for causing severe hemorrhagic fevers. *West Nile virus* - This virus is primarily transmitted by **mosquitoes** and causes **West Nile fever**, which can lead to neurological disease. - It does not cause the hemorrhagic fever associated with Ebola virus disease. *Phlebovirus* - **Phlebovirus** is a genus of viruses that includes several species capable of causing **encephalitis** or **febrile illness** with headache and myalgia. - While some can cause hemorrhagic fevers, it is not the primary agent for the disease specifically known as **Ebola virus disease**. *None of the options* - This option is incorrect because the **Ebola virus** is indeed listed as an option and is the correct pathogen responsible for Ebola virus disease.
Pathology
1 questionsBollinger bodies are seen in ?
NEET-PG 2012 - Pathology NEET-PG Practice Questions and MCQs
Question 691: Bollinger bodies are seen in ?
- A. Chickenpox
- B. Cowpox
- C. Fowlpox (Correct Answer)
- D. Smallpox
Explanation: **IMPORTANT NOTE:** In **human pathology**, the term "Bollinger bodies" classically refers to **sulfur granules** seen in **actinomycosis** (Actinomyces infection), which appear as basophilic masses with radiating eosinophilic clubs. However, this question uses the **veterinary pathology** definition, where Bollinger bodies refer to viral inclusions in avian diseases. ***Fowlpox*** - In **veterinary pathology**, **Bollinger bodies** are characteristic large, eosinophilic **intracytoplasmic inclusion bodies** found in cells infected with the **fowlpox virus** (avipoxvirus). - These inclusions are visible under light microscopy and are a diagnostic feature of **fowlpox**, a widespread avian disease. - Note: Fowlpox is **not a human disease** but affects birds. *Chickenpox* - Chickenpox, caused by the **varicella-zoster virus (VZV)**, is characterized by **intranuclear inclusion bodies** (Cowdry type A) [1]. - It does not form **Bollinger bodies**. *Cowpox* - Cowpox is caused by the **cowpox virus**, an **orthopoxvirus**, and produces **A-type cytoplasmic inclusion bodies** (A-type inclusions). - While these are cytoplasmic inclusions, they are not referred to as **Bollinger bodies**. *Smallpox* - Smallpox, caused by the **variola virus** (orthopoxvirus), is associated with **Guarnieri bodies**, which are **cytoplasmic inclusion bodies**. - These inclusions are distinct from **Bollinger bodies**. **References:** [1] Kumar V, Abbas AK, et al.. Robbins and Cotran Pathologic Basis of Disease. 9th ed. Infectious Diseases, pp. 366-367.