NEET-PG 2012

1213 Questions — Page 23 of 122

Anatomy

5 questions

Q221

Which of the following is a traction epiphysis ?

Q222

Inferior parathyroid develops from which pharyngeal pouch?

Q223

Renal papilla opens into -

Q224

Which of the following statements provides the MOST COMPLETE description of sclerotome function during vertebral development?

Q225

Azygos vein drains into:

NEET-PG 2012 - Anatomy NEET-PG Practice Questions and MCQs

Question 221: Which of the following is a traction epiphysis ?

A. Tibial condyles
B. Head of femur
C. Trochanter of femur
D. Coracoid process of scapula (Correct Answer)

Explanation: ***Coracoid process of scapula*** - A **traction epiphysis** (also called atavistic epiphysis) serves as an attachment site for muscles and tendons, transferring muscle force to the bone without bearing significant weight or forming articular surfaces. - The **coracoid process** is a classic example, anchoring the **pectoralis minor, coracobrachialis, and short head of biceps brachii**, as well as important ligaments (coracoclavicular and coracoacromial). - It develops from a separate ossification center purely for muscle and ligament attachment, not for articulation or weight-bearing. *Tibial condyles* - The **tibial condyles** are **pressure epiphyses** (articular epiphyses) that form the superior articular surface of the tibia. - They articulate with the femoral condyles to form the knee joint and bear significant weight during standing and movement. - Their primary function is joint formation and contribution to longitudinal bone growth. *Trochanter of femur* - The **greater and lesser trochanters** are large bony prominences that serve as muscle attachment sites, but they are better classified as **apophyses** rather than true traction epiphyses. - An **apophysis** is a secondary ossification center that does not contribute to longitudinal bone growth and serves primarily for muscle attachment. - While functionally similar to traction epiphyses, the term "traction epiphysis" is more specifically applied to structures like the coracoid process, tibial tuberosity, and calcaneal tuberosity. *Head of femur* - The **head of femur** is a classic **pressure epiphysis** that articulates with the acetabulum to form the hip joint. - It bears significant body weight and contributes to the longitudinal growth of the femur. - Its primary functions are joint formation and weight transmission, not muscle attachment.

Question 222: Inferior parathyroid develops from which pharyngeal pouch?

A. 1st
B. 2nd
C. 3rd (Correct Answer)
D. 4th

Explanation: The inferior parathyroid glands develop from the dorsal wing of the third pharyngeal pouch. Due to their origin, they often migrate further caudally than the superior parathyroid glands, sometimes even locating within the thymus which also develops from the third pouch. *1st* - The first pharyngeal pouch contributes to the formation of the eustachian tube, tympanic cavity, and mastoid air cells. - It has no role in the development of the parathyroid glands. *2nd* - The second pharyngeal pouch mainly gives rise to the palatine tonsils and their crypts. - It is not involved in the development of parathyroid tissue. *4th* - The fourth pharyngeal pouch gives rise to the superior parathyroid glands and the parafollicular cells (C cells) of the thyroid, which produce calcitonin. - While it forms parathyroid tissue, it is for the superior glands, not the inferior ones.

Question 223: Renal papilla opens into -

A. Cortex
B. Pyramid
C. Minor calyx (Correct Answer)
D. Major calyx

Explanation: ***Minor calyx*** - The **renal papilla** is the apex of the renal pyramid, which drains urine directly into a **minor calyx**. - Minor calyces then merge to form major calyces, eventually leading to the renal pelvis. *Cortex* - The **renal cortex** is the outer layer of the kidney, containing glomeruli and convoluted tubules, and does not directly receive urine from the papilla. - Urine is primarily formed and filtered in the cortex and then flows into the medulla. *Pyramid* - A **renal pyramid** is a conical structure within the renal medulla, and the renal papilla is its tip, but it doesn't open *into* the pyramid itself. - Instead, the pyramid *contains* the structures that contribute to the papilla. *Major calyx* - A **major calyx** is formed by the convergence of several minor calyces. - The renal papilla drains into the minor calyx, which then, in turn, drains into the major calyx.

Question 224: Which of the following statements provides the MOST COMPLETE description of sclerotome function during vertebral development?

A. The notochord forms the nucleus pulposus.
B. The sclerotome contributes to the formation of vertebral bodies.
C. The sclerotome surrounds the notochord and the neural tube during development. (Correct Answer)
D. The sclerotome surrounds the notochord.

Explanation: ***The sclerotome surrounds the notochord and the neural tube during development.*** - The **sclerotome** is the part of the somite that differentiates into mesenchymal cells and migrates to surround both the developing **notochord** (which gives rise to the nucleus pulposus) and the **neural tube** (which forms the spinal cord). - This encirclement is crucial for the formation of the **vertebral column**, providing protection and a structural framework. *The notochord forms the nucleus pulposus.* - While true that the **notochord** contributes to the **nucleus pulposus**, this statement describes the fate of the notochord itself, not the function of the sclerotome. - The question asks for the function of the sclerotome, and this option only details one specific derivative. *The sclerotome contributes to the formation of vertebral bodies.* - This statement is partially true, as the **sclerotome** does indeed form the **vertebral bodies**, arches, and intervertebral discs. - However, it is not the *most complete* description of its function during development, as it omits the crucial aspect of surrounding the neural tube. *The sclerotome surrounds the notochord.* - This statement is correct but **incomplete** as it only mentions the notochord. - The **sclerotome** also surrounds the **neural tube**, which is a vital part of its developmental role in forming the vertebral canal.

Question 225: Azygos vein drains into:

A. Left brachiocephalic vein
B. Inferior vena cava
C. Superior vena cava (Correct Answer)
D. Right brachiocephalic vein

Explanation: Wait, what? Azygos vein drains into: ***Superior vena cava*** - The **azygos vein** ascends along the right side of the vertebral column and typically arches over the root of the right lung before draining into the **superior vena cava (SVC)**. - This anatomical arrangement allows the azygos system to collect venous blood from the posterior thoracic and abdominal walls, as well as the bronchi and esophagus, ultimately returning it to the systemic circulation via the SVC [1]. *Left brachiocephalic vein* - The **left brachiocephalic vein** drains blood from the upper left limb and left side of the head and neck. - It merges with the right brachiocephalic vein to form the SVC; the azygos vein does not directly drain into it. *Inferior vena cava* - The **inferior vena cava (IVC)** collects deoxygenated blood from the lower body. - The azygos system primarily drains structures above the diaphragm, distinct from the IVC's drainage area. *Right brachiocephalic vein* - The **right brachiocephalic vein** drains blood from the upper right limb and right side of the head and neck. - While it contributes to the formation of the SVC, the azygos vein's direct connection is to the SVC itself, not the right brachiocephalic vein.

Biochemistry

2 questions

Q221

What are digestive enzymes classified as?

Q222

What is the specific activity of an enzyme?

NEET-PG 2012 - Biochemistry NEET-PG Practice Questions and MCQs

Question 221: What are digestive enzymes classified as?

A. Hydrolases (Correct Answer)
B. Oxidoreductases
C. Transferases
D. Ligases

Explanation: ***Hydrolases*** - Digestive enzymes like **amylase**, **lipase**, and **proteases** break down complex food molecules by adding water, a process known as **hydrolysis**. - This class of enzymes catalyzes the cleavage of a chemical bond with the concurrent addition of a water molecule. - All major digestive enzymes belong to this class according to the **EC enzyme classification system**. *Oxidoreductases* - These enzymes catalyze **redox reactions**, involving the transfer of electrons from one molecule to another. - Examples include **dehydrogenases** and **oxidases**, which are not primarily involved in breaking down food molecules in digestion. *Transferases* - Transferases catalyze the transfer of functional groups (such as methyl, acyl, or phosphate groups) from one molecule to another. - Examples include **kinases** and **transaminases**, which are involved in metabolic pathways but not in the digestive breakdown of food. *Ligases* - Ligases are enzymes that catalyze the joining of two large molecules by forming a new chemical bond, typically with the concomitant hydrolysis of ATP. - They are involved in **DNA repair** and **biosynthetic reactions**, not in the breakdown of food during digestion.

Question 222: What is the specific activity of an enzyme?

A. Enzyme units per mg of protein (Correct Answer)
B. Concentration of substrate transformed per minute
C. Enzyme units per mg of substrate
D. Limit of enzyme per gram of substrate

Explanation: ***Enzyme units per mg of protein*** - **Specific activity** is defined as the number of **enzyme units** (representing catalytic activity) per milligram of total protein in the sample. - It is a measure of **purity**, indicating the amount of active enzyme relative to other proteins in a preparation. - Formula: Specific activity = Units of enzyme activity / mg of total protein - Used to track enzyme purification progress during isolation procedures. *Concentration of substrate transformed per minute* - This describes the **reaction velocity** or rate of catalysis, but not the specific activity of the enzyme. - While related to enzyme activity, it does not normalize the activity to the amount of **total protein**. - This would be expressed as reaction rate or velocity (V), not specific activity. *Enzyme units per mg of substrate* - This is an incorrect formulation that confuses substrate with protein. - **Specific activity** is normalized to the amount of **protein** in the enzyme preparation, not the substrate. - This option represents a common misconception in enzyme kinetics terminology. *Limit of enzyme per gram of substrate* - This phrase does not correspond to any standard biochemical measure of enzyme activity or concentration. - It does not provide information about the **catalytic efficiency** or **purity** of the enzyme preparation. - The term "limit" is not used in the context of specific activity measurements.

Obstetrics and Gynecology

1 questions

Q221

Blastocyst makes contact with endometrium on ?

Physiology

2 questions

Q221

When the tension in a muscle fibre is maximum, its length is called?

Q222

Which of the following is the MOST accurate statement about CSF?

NEET-PG 2012 - Physiology NEET-PG Practice Questions and MCQs

Question 221: When the tension in a muscle fibre is maximum, its length is called?

A. None of the options
B. Initial length
C. Equilibrium length
D. Optimum length (Correct Answer)

Explanation: ***Optimum length*** - This is the muscle length at which the **maximum number of cross-bridges** can form between actin and myosin filaments. - At this length, the sarcomere allows for the **greatest overlap** of thick and thin filaments without excessive stretching or compression, leading to peak tension generation. *Equilibrium length* - This term usually refers to the **resting length** of a muscle fiber when no external forces are acting upon it. - At equilibrium, the tension generated by the muscle may not necessarily be at its maximum. *Initial length* - This is a general term that refers to the **starting length** of a muscle fiber before it contracts or is stretched. - It does not specifically denote the length at which maximum tension is achieved. *None of the options* - This option is incorrect because **optimum length** accurately describes the muscle length yielding maximum tension.

Question 222: Which of the following is the MOST accurate statement about CSF?

A. Formed by the choroid plexus in the ventricles. (Correct Answer)
B. Normally contains no neutrophils
C. pH is less than that of plasma
D. Removal of CSF during dural tap can cause a headache due to the change in pressure.

Explanation: ***Formed by the choroid plexus in the ventricles.*** * The **choroid plexus**, located in the ventricles of the brain, is primarily responsible for the production of **cerebrospinal fluid (CSF)**. * Specialized epithelial cells of the choroid plexus filter blood plasma to produce CSF, which then circulates through the central nervous system. *Normally contains no neutrophils* * Normal CSF should contain **virtually no neutrophils**; their presence typically indicates an inflammatory or infectious process, such as **bacterial meningitis**. * While normal CSF doesn't have neutrophils, this option isn't as broadly accurate as the choroid plexus statement because the presence of other cell types like lymphocytes in small numbers is normal. *pH is less than that of plasma* * The pH of CSF is typically **slightly lower than that of plasma** (around 7.31 compared to 7.40), but the statement "less than" is broad and the degree of difference can be variable and is a less defining characteristic than its formation site. * This slight difference in pH is important for regulating **respiration** through chemoreceptors, but it's not the most accurate or fundamental statement about CSF properties. *Removal of CSF during dural tap can cause a headache due to the change in pressure.* * A **post-dural puncture headache** (PDPH) is a well-known complication of a dural tap (lumbar puncture), caused by the leakage of CSF from the puncture site, leading to **intracranial hypotension**, not simply a change in pressure. * This decrease in CSF volume and pressure causes a traction on pain-sensitive structures within the cranium, resulting in a headache that is typically **worse when upright** and relieved by lying down.