NEET-PG 2012 Practice Questions

Q: Which condition is associated with calcification of the intervertebral disc?

Alkaptonuria. ***Alkaptonuria*** - **Alkaptonuria** is a rare autosomal recessive disorder characterized by a deficiency of the enzyme **homogentisate 1,2-dioxygenase**, leading to the accumulation of **homogentisic acid**. - This accumulation results in the deposition of a **dark pigment (ochre pigment)** in connective tissues, including the intervertebral discs, causing **calcification (ochronosis)** and early degenerative arthritis. *Gout* - **Gout** is caused by the deposition of **monosodium urate crystals** in joints and soft tissues, leading to inflammation and pain [1]. - While it can affect various joints, it does not typically cause **calcification of intervertebral discs**; rather, it can form tophi in periarticular soft tissues [1]. *Rheumatoid* - **Rheumatoid arthritis** is a chronic autoimmune inflammatory disease primarily affecting the **synovial lining of joints**, leading to joint destruction and deformity. - It does not involve the **calcification of intervertebral discs**; spinal involvement is usually restricted to the cervical spine, particularly the atlantoaxial joint. *Psoriasis* - **Psoriasis** is a chronic inflammatory skin condition, which in some cases can be associated with **psoriatic arthritis**, an inflammatory arthritis. - Psoriatic arthritis primarily affects peripheral joints, the sacroiliac joints, and the spine, but it does not cause **calcification of the intervertebral discs** as seen in alkaptonuria.

Q: What condition is primarily diagnosed using Von Rosen's view?

Congenital dislocation of the hip (CDH). ***Congenital dislocation of the hip (CDH)*** - **Von Rosen's view** is a specialized X-ray projection used specifically to assess for **developmental dysplasia of the hip (DDH)**, also known as CDH, in infants. - This view helps visualize the relationship between the **femoral head** and the **acetabulum** by positioning the infant's hips in extension, abduction, and internal rotation. *Perthes disease* - **Perthes disease** is an avascular necrosis of the femoral head, typically diagnosed with standard **frog-leg lateral** and **AP pelvic X-rays**. - While it affects the hip, Von Rosen's view is not the primary diagnostic imaging for this condition, which usually presents later in childhood. *Congenital Talipes Equinovarus (CTEV)* - **CTEV**, or **clubfoot**, is a deformity of the foot and ankle, not the hip. - It is primarily diagnosed clinically and then confirmed with **AP and lateral X-rays of the foot** to assess bone alignment. *None of the options* - This option is incorrect because **Congenital dislocation of the hip (CDH)** is indeed primarily diagnosed using Von Rosen's view, among other methods.

Q: What does the term 'etheromania' refer to?

Ether addiction. ***Ether addiction*** - **Etheromania** specifically refers to the compulsive use and dependence on **ether** for its psychoactive effects. - This term was historically used to describe individuals who developed a significant **addiction** to ether. - The suffix "-mania" in psychiatric terminology often denotes an obsessive or compulsive behavior pattern related to a specific substance. *Acute psychosis following ether anesthesia* - While ether anesthesia can sometimes lead to transient psychomotor agitation or emergence delirium, **acute psychosis** is not the primary definition of etheromania. - Etheromania describes a long-term pattern of **addictive behavior**, not an acute post-anesthesia complication. *Excessive use of ether as an anesthetic* - This describes a medical application of ether, albeit potentially misused, but does not primarily denote the **addictive state** of the person using it. - **Etheromania** focuses on the individual's psychological and physiological dependence, not merely the quantity used for medical purposes. *Delirium tremens from ether withdrawal* - Delirium tremens is specifically associated with **alcohol withdrawal**, not ether withdrawal. - While ether withdrawal can cause symptoms, the term **etheromania** refers to the addiction itself, not withdrawal complications.

Q: Which of the following is a recognized type of anxiety disorder?

Panic Disorder. ***Panic Disorder*** - **Panic disorder** is a recognized **anxiety disorder** characterized by recurrent unexpected **panic attacks** - sudden episodes of intense fear accompanied by physical symptoms like heart palpitations, shortness of breath, chest pain, dizziness, and trembling. - It involves persistent worry about having more attacks (anticipatory anxiety) and maladaptive behavioral changes to avoid situations where attacks might occur. - Classified under **Anxiety Disorders** in DSM-5 and ICD-11. *Major Depressive Disorder* - **Major Depressive Disorder (MDD)** is a **mood disorder**, not an anxiety disorder. - Characterized by persistent depressed mood, loss of interest or pleasure (anhedonia), changes in appetite/sleep, fatigue, feelings of worthlessness, and potential suicidal ideation. - Classified under **Depressive Disorders** in DSM-5, distinct from anxiety disorders, though anxiety symptoms may co-occur. *Bipolar Disorder* - **Bipolar disorder** is a **mood disorder**, not an anxiety disorder. - Characterized by significant mood swings including episodes of mania/hypomania (elevated, expansive, or irritable mood with increased energy) and depression. - Classified under **Bipolar and Related Disorders** in DSM-5, distinct from anxiety disorders. *Schizophrenia* - **Schizophrenia** is a **psychotic disorder**, not an anxiety disorder. - Characterized by disturbances in thought, perception, emotions, and behavior, including hallucinations, delusions, disorganized thinking, and negative symptoms. - Classified under **Schizophrenia Spectrum and Other Psychotic Disorders** in DSM-5, distinct from anxiety disorders.

Q: Derealization and depersonalization are symptoms of which type of disorder?

Dissociative disorder. ***Dissociative disorder*** - **Derealization** involves experiencing the outside world as unreal or dreamlike - **Depersonalization** is the experience of feeling detached from one's own body or mental processes - These are hallmark symptoms of **dissociative disorders**, specifically depersonalization-derealization disorder in DSM-5 *Personality disorders* - Characterized by enduring, maladaptive patterns of inner experience and behavior - While some personality disorders (e.g., **borderline personality disorder**) may display transient dissociative symptoms under stress, derealization and depersonalization are not core diagnostic features *Mania* - A state of abnormally elevated mood and energy, involving **racing thoughts**, **decreased need for sleep**, and **impulsive behavior** - Does not typically involve consistent derealization or depersonalization as core features *Anxiety disorders* - Depersonalization can occur transiently during **panic attacks** or severe anxiety - However, when derealization and depersonalization are the primary, persistent symptoms, they indicate a **dissociative disorder** rather than an anxiety disorder

Q: Investigation of choice for screening of proximal internal carotid artery stenosis is :

Doppler ultrasound (USG). ***Doppler ultrasound (USG)*** - **Doppler ultrasound** is the investigation of choice for screening carotid artery stenosis due to its **non-invasive nature**, widespread availability, and cost-effectiveness. It provides excellent anatomical information and hemodynamics, including **blood flow velocity** and presence of **plaque**. - It can effectively estimate the degree of **stenosis** based on flow characteristics and is safe for serial monitoring. *CT angiography* - **CT angiography** provides detailed anatomical imaging of the carotid arteries but involves **ionizing radiation** and **iodinated contrast agents**, making it less suitable for routine screening, especially in patients with renal impairment or contrast allergies. - While it offers higher resolution for certain plaque characteristics, it’s typically reserved for cases where ultrasound findings are inconclusive or for surgical planning. *Magnetic resonance imaging (MRI)* - **MRI** and **MR angiography (MRA)** can visualize carotid stenosis without ionizing radiation but are more expensive and time-consuming than ultrasound, and can be limited by artifacts from patient movement. - Patients with **claustrophobia** or **metallic implants** may not be suitable for MRI, making it less ideal for general screening. *Digital subtraction angiography (DSA)* - **Digital subtraction angiography (DSA)** is the **gold standard** for diagnosing carotid stenosis as it provides the most detailed and accurate images of the arterial lumen. However, it is an **invasive procedure** associated with risks such as stroke, arterial dissection, contrast nephropathy, and radiation exposure. - Due to its invasiveness and potential complications, DSA is typically reserved for cases with **discordant non-invasive findings** or prior to intervention rather than as a primary screening tool.

Q: HU is a measure of

CT. ***Correct Answer: CT*** - HU stands for **Hounsfield Units**, a standardized quantitative scale used exclusively in **computed tomography (CT)** to describe the **radiodensity** of tissues based on **X-ray attenuation**. - On this scale, **water is assigned 0 HU**, air is -1000 HU, and dense bone can be +1000 HU or more. - This allows objective measurement and comparison of tissue densities across different CT scanners and examinations. *Incorrect: MRI* - **Magnetic Resonance Imaging (MRI)** does not use Hounsfield Units. - MRI signal intensity is based on the **magnetic properties of tissues** and local hydrogen proton density, not X-ray attenuation. *Incorrect: PET* - **Positron Emission Tomography (PET)** measures the metabolic activity of cells using **radioactive tracers**. - Its output is typically quantified in **Standardized Uptake Value (SUV)**, not Hounsfield Units. *Incorrect: USG* - **Ultrasound (USG)** imaging uses sound waves to create images of internal body structures. - It measures the **acoustic impedance** of tissues and displays findings in terms of echogenicity, not Hounsfield Units.

Q: Which of the following appears the same on both T1 and T2 weighted MRI sequences?

Fat. ***Fat*** - On both T1 and T2 weighted MRI sequences, fat appears **bright** (high signal intensity). - This consistent bright signal makes fat a useful internal reference point for signal interpretation. *Gall bladder* - The gall bladder is filled with **bile**, which appears bright on T2-weighted images due to its high water content, but can be variable on T1. - Bile does not maintain consistently the **same signal intensity** as fat on both sequences. *Kidney* - The renal parenchyma typically has **intermediate signal intensity** on both T1 and T2, but its signal characteristics are different from the consistently bright signal of fat. - The signal can vary depending on the specific sequence parameters and hydration status, unlike fat. *CSF* - **Cerebrospinal fluid (CSF)** appears dark (low signal) on T1-weighted images and bright (high signal) on T2-weighted images due to its high water content. - This distinct signal intensity difference between T1 and T2 is contrary to the shared bright appearance of fat on both sequences.

Q: Which of the following features is used to identify the colon on an X-ray?

Haustra. ***Haustra (Correct Answer)*** - **Haustra** are sacculations or pouches of the colon created by the uneven contraction of the **taeniae coli** - They are THE characteristic feature that helps distinguish the large bowel from the small bowel on an X-ray - These indentations typically do **not cross the entire width** of the bowel lumen, unlike the valvulae conniventes of the small intestine - Haustra appear as incomplete septations on plain radiographs *Valvulae conniventes (Incorrect)* - **Valvulae conniventes** (also known as plicae circulares) are large, circular folds of the **small intestine** mucosa that project into the lumen - They extend **completely across the lumen** of the small bowel, making them easily distinguishable from haustra which only partially traverse the colon - This is a feature of small bowel, not colon *String of beads sign (Incorrect)* - The "**string of beads sign**" is a **pathological radiographic finding** associated with small bowel obstruction - It refers to multiple small, gas-filled loops of small bowel stacked on top of each other, often with small pockets of fluid or air trapped between the folds, resembling beads on a string - This is not a normal anatomical feature used to identify the colon *More number of loops (Incorrect)* - The number of loops is **not a primary distinguishing feature** between the large and small bowel on an X-ray - While the small intestine generally has more convolutions or loops than the colon, this is a **less reliable and specific sign** compared to the presence of haustra - Haustra remain the gold standard feature for colon identification

Q: Investigation of choice for studying Renal Cortical mass

99mTc DMSA. ***99mTc DMSA*** - **99mTc DMSA** (Technetium-99m dimercaptosuccinic acid) is the radiopharmaceutical of choice for imaging the **renal cortex** and assessing **renal cortical mass** and scarring. - It binds preferentially to the cells of the **renal tubules**, allowing for excellent visualization of cortical tissue. *99mTc DTPA* - **99mTc DTPA** (Technetium-99m Diethylenetriaminepentaacetic acid) is primarily used to assess **glomerular filtration rate (GFR)** and renal blood flow. - It is filtered by the **glomeruli** but not reabsorbed or secreted by the tubules, making it suitable for functional studies rather than morphological assessment of cortical mass. *53Cr Study* - **53Cr** (Chromium-51) is used in studies to measure **red blood cell mass**, survival, or gastrointestinal protein loss. - It has no role in the direct assessment of **renal cortical mass** or function. *99mTc Pyrophosphate* - **99mTc Pyrophosphate** is primarily used to evaluate **myocardial infarction** (hot spots) or detect bone lesions. - It is not indicated for, nor does it provide useful information about, **renal cortical mass**.

Question 1

Which condition is associated with calcification of the intervertebral disc?

Accepted Answer

Alkaptonuria

Answer

Gout

Answer

Rheumatoid

Answer

Psoriasis

Question 2

What condition is primarily diagnosed using Von Rosen's view?

Accepted Answer

Congenital dislocation of the hip (CDH)

Answer

Perthes disease

Answer

Congenital Talipes Equinovarus (CTEV)

Answer

None of the options

Question 3

What does the term 'etheromania' refer to?

Accepted Answer

Ether addiction

Answer

Acute psychosis following ether anesthesia

Answer

Excessive use of ether as an anesthetic

Answer

Delirium tremens from ether withdrawal

Question 4

Which of the following is a recognized type of anxiety disorder?

Accepted Answer

Panic Disorder

Answer

Bipolar Disorder

Answer

Major Depressive Disorder

Answer

Schizophrenia

Question 5

Derealization and depersonalization are symptoms of which type of disorder?

Accepted Answer

Dissociative disorder

Answer

Personality disorders

Answer

Mania

Answer

Anxiety disorders

Question 6

Investigation of choice for screening of proximal internal carotid artery stenosis is :

Accepted Answer

Doppler ultrasound (USG)

Answer

CT angiography

Answer

Magnetic resonance imaging (MRI)

Answer

Digital subtraction angiography (DSA)

Question 7

HU is a measure of

Accepted Answer

CT

Answer

MRI

Answer

PET

Answer

USG

Question 8

Which of the following appears the same on both T1 and T2 weighted MRI sequences?

Accepted Answer

Fat

Answer

Gall bladder

Answer

Kidney

Answer

CSF

Question 9

Which of the following features is used to identify the colon on an X-ray?

Accepted Answer

Haustra

Answer

Valvulae conniventes

Answer

String of beads sign

Answer

More number of loops

Question 10

Investigation of choice for studying Renal Cortical mass

Accepted Answer

99mTc DMSA

Answer

99mTc DTPA

Answer

53Cr Study

Answer

99mTc Pyrophosphate

NEET-PG 2012

Internal Medicine

Orthopaedics

Psychiatry

Radiology