Ochronosis is seen in poisoning with:

Carbolic acid. ***Carbolic acid (Phenol)*** - Carbolic acid causes **blackish-brown discoloration** of skin and tissues at the site of contact due to its **corrosive action and protein denaturation**. - This characteristic **dark staining of tissues** is a forensic marker of phenol poisoning and is sometimes referred to in forensic literature as "ochronosis-like" changes. - Phenol is absorbed through skin and mucous membranes and can cause **CNS depression, convulsions, and metabolic acidosis**. *Boric acid* - Boric acid poisoning manifests with **"boiled lobster" appearance** of skin (erythematous desquamation). - Causes **gastrointestinal symptoms** (vomiting, diarrhea) and **CNS effects** in severe cases. - Does not cause blackish tissue discoloration. *HCl (Hydrochloric acid)* - HCl is a **strong corrosive acid** causing severe chemical burns. - Produces **white or gray coagulated necrosis** of tissues on contact. - Does not produce the dark discoloration characteristic of phenol. *Oxalic acid* - Oxalic acid poisoning causes **hypocalcemia** by chelating calcium ions. - Leads to **cardiac arrhythmias, tetany, and renal toxicity** (calcium oxalate crystal deposition). - Does not cause tissue discoloration or ochronosis.

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NEET-PG 2012 — Forensic Medicine

41 Questions — Page 5 of 5