The inducing agent of choice in shock -

Ketamine. **Ketamine** * **Ketamine** is preferred in shock due to its sympathomimetic properties, which maintain or increase blood pressure and heart rate, thus preserving **cardiovascular stability**. * It also has minimal respiratory depression and bronchodilatory effects, making it safer for patients with compromised respiratory function. * The cardiovascular stimulating effects of ketamine helps maintain haemodynamic stability in shocked patients. It maintains cerebral autoregulation and perfusion of vital organs. *Isoflurane* * **Isoflurane** is an inhaled anesthetic that typically causes **dose-dependent myocardial depression** and **vasodilation**, which can worsen hypotension in a shock state. * It can significantly decrease systemic vascular resistance, thereby exacerbating the already compromised cardiovascular status of a shock patient. *Desflurane* * **Desflurane** is an inhaled anesthetic known for its rapid onset and offset but can cause a **significant increase in heart rate and blood pressure** upon rapid concentration changes, which may be detrimental in an unstable patient. * Like isoflurane, it also causes dose-dependent peripheral vasodilation and myocardial depression, which can worsen hypotension in patients in shock. *Thiopentone* * **Thiopentone** is a barbiturate that causes significant **myocardial depression** and **peripheral vasodilation**, leading to a substantial drop in blood pressure. * Its use in shock would further compromise cardiovascular stability and is generally contraindicated due to its potent hemodynamic depressant effects.

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NEET-PG 2012 — Anesthesiology

21 Questions — Page 3 of 3