UPSC-CMS 2014 - Pathology PYQs Practice Questions

Q: Which one of the following is not an epithelial tumour of the ovary?

Endodermal sinus tumour. ***Endodermal sinus tumour*** - This is a type of **germ cell tumor** of the ovary, not an epithelial tumor. - It is characterized by the presence of **Schiller-Duval bodies** and elevated **alpha-fetoprotein (AFP)** levels. *Clear cell tumour* - This is a well-recognized sub-type of **epithelial ovarian cancer**, often associated with **endometriosis** [1]. - The histology typically shows cells with clear cytoplasm, sometimes arranged in glandular or tubulocystic patterns [1]. *Serous cystadenoma* - This is a common **benign epithelial tumor** of the ovary, characterized by cysts lined by serous epithelium [2]. - It arises from the **surface epithelium** of the ovary. *Brenner's tumour* - This is a less common but distinct type of **epithelial ovarian tumor**, characterized by nests of **transitional epithelial cells** resembling bladder urothelium [3]. - It is usually **benign** and often discovered incidentally [3]. **References:** [1] Kumar V, Abbas AK, et al.. Robbins and Cotran Pathologic Basis of Disease. 9th ed. The Female Genital Tract, p. 1032. [2] Cross SS. Underwood's Pathology: A Clinical Approach. 6th ed. Common Clinical Problems From Female Genital Tract Disease, pp. 478-480. [3] Kumar V, Abbas AK, et al.. Robbins and Cotran Pathologic Basis of Disease. 9th ed. The Female Genital Tract, pp. 1032-1033. [Practice more Pathology PYQs on OnCourse]

Q: In which of the following is the term low and high grade squamous intraepithelial neoplasia used?

Bethesda classification. ***Bethesda classification*** - The Bethesda classification system is used for reporting **cervical cytology** results (Pap test) [1]. - It categorizes squamous cell abnormalities into **low-grade squamous intraepithelial lesion (LSIL)** and **high-grade squamous intraepithelial lesion (HSIL)** [1]. *Shaw's classification* - **Shaw's classification** is not a recognized system for reporting cervical cytopathology. - This term does not apply to the categorization of squamous intraepithelial neoplasia. *FIGO staging* - **FIGO (International Federation of Gynecology and Obstetrics) staging** is used for the clinical staging of **gynecologic cancers**, not for initial cytological screening results [1]. - It describes the extent of cancer progression, not intraepithelial lesions. *Papanicolaou method* - The **Papanicolaou (Pap) method** refers to the staining technique and the general cytological test for cervical cancer screening [1]. - While it's the test itself, the **interpretation and reporting** of results, including terms like LSIL and HSIL, fall under the Bethesda classification system [1]. **References:** [1] Kumar V, Abbas AK, et al.. Robbins and Cotran Pathologic Basis of Disease. 9th ed. The Female Genital Tract, pp. 1006-1010. [Practice more Pathology PYQs on OnCourse]

Question 1

Which of the following pairs is not correctly matched?

Accepted Answer

Sister Joseph’s nodule ……… Solitary secondary deposit in the liver

Answer

Krukenberg tumour ……… Peritoneal seeding involving ovaries

Answer

Virchow’s node ……… Palpable node in left supraclavicular space

Answer

Blumer’s shelf ……… Secondary deposits in pelvic cul-de-sac

Question 2

Which one of the following is not an epithelial tumour of the ovary?

Accepted Answer

Endodermal sinus tumour

Answer

Clear cell tumour

Answer

Serous cystadenoma

Answer

Brenner’s tumour

Question 3

In which of the following is the term low and high grade squamous intraepithelial neoplasia used?

Accepted Answer

Bethesda classification

Answer

Shaw's classification

Answer

FIGO staging

Answer

Papanicolaou method

UPSC-CMS 2014 — Pathology