Antibiotics — Flashcards

Flashcard 931: Proteasomal inhibitors work best in cancers that mark _____ proteins to be targeted for degradation too quickly

Answer: pro-apoptotic

Flashcard 932: Which aminoglycoside treats tularemia caused by Francisella tularensis?

Answer: Streptomycin

Flashcard 933: _____ is a macrolide antibiotic that can be used to treat diptheria caused by Corynebacterium diphtheriae.

Answer: Erythromycin

Flashcard 934: _____ is an antibiotic that is avoided in pregnancy as it causes "Gray Baby" Syndrome.

Answer: Chloramphenicol

Flashcard 935: Aminopenicillin used as part of Helicobacter pylori triple therapy_____

Answer: Amoxicillin

Flashcard 936: What is the treatment for Nocardia spp. infection?_____

Answer: Sulfonamides

Flashcard 937: 1st generation cephalosporins that can be used to treat skin and soft tissue infections by Staph and Strep_____

Answer: Cephalexin, Cefazolin

Flashcard 938: Which step of bacterial protein synthesis does Chloramphenicol inhibit?

Answer: Peptidyl transferase (50S subunit)

Extra: Chloramphenicol binds to the 50S ribosomal subunit and inhibits the peptidyl transferase enzyme, preventing peptide bond formation. It is generally bacteriostatic.

Flashcard 939: 1st generation cephalosporins have activity mostly against gram-_____ organisms

Answer: positive

Flashcard 940: Red man syndrome is characterized by histamine release with possible _____-tension

Answer: hypo