Antibiotics — Flashcards

Flashcard 921: Sulfonylureas are _____ drugs and thus may cause adverse reactions in allergic patients

Answer: sulfa

Flashcard 922: Which step of bacterial protein synthesis do aminoglycosides primarily inhibit?

Answer: Formation of the initiation complex (by binding to the 30S ribosomal subunit)

Extra: Aminoglycosides also cause misreading of mRNA and inhibit translocation. They are unique among protein synthesis inhibitors for being bactericidal.

Flashcard 923: Less commonly, Fluoroquinolones cause _____pathy

Answer: myo

Flashcard 924: What is first-line in the treatment of Clostridium difficile?_____

Answer: Oral Vancomycin

Flashcard 925: Erythromycin is used off-label for the treatment of gastro-_____

Answer: paresis

Flashcard 926: _____ may increase the serum concentration of theophylline or oral anticoagulants

Answer: Macrolides

Flashcard 927: What is the most common adverse effect of Clindamycin?_____

Answer: Diarrhea

Flashcard 928: Which bacterial protein synthesis inhibitor can cause thrombocytopenia (beside chloramphenicol)?_____

Answer: Linezolid

Flashcard 929: Red man syndrome can be avoided by _____ the infusion of vancomycin

Answer: slowing

Flashcard 930: _____ can predispose individuals to vaginal yeast infections

Answer: Antibiotics and OCPs (oral contraceptives) (which 2 classes of medications)