Antibiotics — Flashcards

Flashcard 941: Are Tetracyclines indicated for patients who are experiencing symptoms of Meningitis?_____

Answer: No

Flashcard 942: What is one specific gram negative rod carbapenems treat?_____

Answer: Pseudomonas

Flashcard 943: Which step of bacterial protein synthesis does Chloramphenicol inhibit?

Answer: Peptidyl transferase (50S subunit)

Extra: Chloramphenicol binds to the 50S ribosomal subunit and inhibits the peptidyl transferase enzyme, preventing peptide bond formation. It is generally bacteriostatic.

Flashcard 944: What is the first-line treatment of complicated UTIs?_____

Answer: Fluoroquinolones

Flashcard 945: What is the treatment for Nocardia spp. infection?_____

Answer: Sulfonamides

Flashcard 946: 1st generation cephalosporins have activity mostly against gram-_____ organisms

Answer: positive

Flashcard 947: Carbapenems may cause skin _____

Answer: rash

Flashcard 948: Fluoroquinolone side effects (ex. GI upset) are most likely mediated by _____ toxicity

Answer: mitochondrial

Flashcard 949: Fluoroquinolones are contraindicated in the following groups due to damage to _____- people > 60 years old- patients taking prednisone

Answer: tendons

Flashcard 950: Which antibiotics can result in acute tubular necrosis?_____

Answer: Aminoglycosides