Antibiotics — Flashcards

Flashcard 571: Vitamin K deficiency may occur due to long-term _____ therapy, which disrupts the gut flora

Answer: antibiotic

Flashcard 572: Which enzyme is inhibited by trimethoprim (TMP)?_____

Answer: Dihydrofolate reductase (prokaryotic)

Flashcard 573: Mutations in which bacterial enzyme can result in resistance to Rifampin?

Answer: DNA-dependent RNA polymerase

Flashcard 574: Does the 5th generation cephalosporin ceftaroline have Pseudomonas coverage?

Answer: No

Extra: While the 4th generation cephalosporin (cefepime) covers Pseudomonas, the 5th generation (ceftaroline) does not. Note: Newer agents like ceftobiprole may have activity, but for exam purposes, ceftaroline is the 5th generation prototype and lacks anti-pseudomonal activity.

Flashcard 575: Reversible inhibition of growthBacterio-_____

Answer: static

Flashcard 576: Sulfonamides increase the risk of _____ when taken along with Warfarin

Answer: bleeding

Flashcard 577: Which etiology of meningitis is Pyrazinamide prescribed to treat?_____

Answer: M. tuberculosis

Flashcard 578: What is the susceptibility of monobactams (aztreonam) to beta-lactamases?_____

Answer: Resistant

Flashcard 579: Isoniazid therapy indirectly decreases vitamin _____ by decreasing levels of vitamin B6

Answer: B3

Flashcard 580: Which bacterial ribosomal subunit is targeted by Chloramphenicol?_____

Answer: 50S