Antibiotics US Medical PG Flashcards - Medical Study Cards
Master Antibiotics with OnCourse flashcards. These spaced repetition flashcards are designed for medical students preparing for NEET PG, USMLE Step 1, USMLE Step 2, MBBS exams, and other medical licensing examinations.
Antibiotics Flashcard Deck - 10 Cards
Flashcard 41: Sulfonamides displace unconjugated bilirubin from albumin; can precipitate _____ in neonates
Answer: kernicterus
Extra:
Watch Trimethoprim/Sulfamethoxazole [https://dashboard.sketchy.com/study/medical/courses/medical-pharmacology/units/medical-pharmacology-antimicrobials/videos/medical-pharmacology-antimicrobials-other-antibiotics-trimethoprimsulfamethoxazole?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical]
https://onlinemeded.org/spa/infectious-disease?ref=anki
Flashcard 42: Which Aminopenicillin is used as part of Helicobacter pylori triple therapy?
_____
Answer: Amoxicillin
Extra:
https://onlinemeded.org/spa/infectious-disease?ref=anki
Flashcard 43: What structural feature of Penicillins give them their activity?
_____
Answer: B-lactam ring
Extra: The beta-lactam core of the molecule irreversibly binds (acetylates) a serine residue of the Transpeptidase active site. Acetylation of this site makes transpeptidases inactive, preventing cross-linking of the newly formed peptidoglycan layer.
Flashcard 44: Fluoroquinolones are indicated mostly for gram _____ infections
Answer: negative
Extra:
Watch Fluoroquinolones [https://dashboard.sketchy.com/study/medical/courses/medical-pharmacology/units/medical-pharmacology-antimicrobials/videos/medical-pharmacology-antimicrobials-other-antibiotics-fluoroquinolones?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical]
https://onlinemeded.org/spa/infectious-disease/pneumonia/acquire?ref=anki
Flashcard 45: Penicillin binds to PBP transpeptidases by mimicking the _____ sequence of peptidoglycan
Answer: D-ala-D-ala
Extra:
Watch Penicillin [https://dashboard.sketchy.com/study/medical/courses/medical-pharmacology/units/medical-pharmacology-antimicrobials/videos/medical-pharmacology-antimicrobials-cell-wall-and-membrane-active-antibiotics-penicillin?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical]
https://onlinemeded.org/spa/infectious-disease?ref=anki
Flashcard 46: _____ is a type of β-lactamase that cleaves penicillins
Answer: Penicillinase
Extra:
Watch Penicillin [https://dashboard.sketchy.com/study/medical/courses/medical-pharmacology/units/medical-pharmacology-antimicrobials/videos/medical-pharmacology-antimicrobials-cell-wall-and-membrane-active-antibiotics-penicillin?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical]
https://onlinemeded.org/spa/infectious-disease?ref=anki
Flashcard 47: Trimethoprim inhibits the enzyme _____
Answer: Dihydrofolate Reductase
Extra:
https://onlinemeded.org/spa/infectious-disease?ref=anki
Flashcard 48: Resistance to Sulfonamides is primarily developed via a mutation of _____
Answer: bacterial dihydropteroate synthase
Extra:
https://onlinemeded.org/spa/infectious-disease?ref=anki
Flashcard 49: Tetracyclines are very effective against Rickettsia and Chlamydophila because these drugs _____
Answer: accumulate intracellularly
Extra:
https://onlinemeded.org/spa/infectious-disease?ref=anki
Flashcard 50: Are aminopenicillins (amoxicillin, ampicillin) sensitive to β-lactamases?
_____
Answer: Yes!
Extra:
https://onlinemeded.org/spa/infectious-disease?ref=anki
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