Antibiotics US Medical PG Flashcards - Medical Study Cards
Master Antibiotics with OnCourse flashcards. These spaced repetition flashcards are designed for medical students preparing for NEET PG, USMLE Step 1, USMLE Step 2, MBBS exams, and other medical licensing examinations.
Antibiotics Flashcard Deck - 10 Cards
Flashcard 31: Clindamycin prevents translocation by binding the 50S ribosome and sterically hindering _____
Answer: peptidyl transfer
Extra:
https://onlinemeded.org/spa/infectious-disease?ref=anki
Flashcard 32: Tetracyclines inhibit bacterial protein synthesis by binding to the _____ subunit and preventing attachment of aminoacyl-tRNA to the A-site.
Answer: 30S
Flashcard 33: Rifamycins inhibit which bacterial enzyme?\n_____
Answer: DNA-dependent RNA polymerase
Extra: Rifamycins bind to the β-subunit of bacterial DNA-dependent RNA polymerase, inhibiting RNA synthesis. They do not affect eukaryotic RNA polymerase.
Flashcard 34: What gout drug can precipitate the side effects of penicillins?
_____
Answer: Probenecid
Extra:
https://onlinemeded.org/spa/infectious-disease?ref=anki
Flashcard 35: Linezolid is a weak MAO inhibitor, thus predisposing patients to _____
Answer: serotonin syndrome
Extra:
Watch Linezolid [https://dashboard.sketchy.com/study/medical/courses/medical-pharmacology/units/medical-pharmacology-antimicrobials/videos/medical-pharmacology-antimicrobials-inhibitors-of-bacterial-protein-synthesis-linezolid?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical] Watch associated Bootcamp video [https://app.bootcamp.com/med-school/psychiatry/videos/pharmacology?index=17]
https://onlinemeded.org/spa/infectious-disease?ref=anki
Flashcard 36: Rifabutin _____ cytochrome p450
Answer: induces
Extra:
Watch Leprosy drugs [https://dashboard.sketchy.com/study/medical/courses/medical-pharmacology/units/medical-pharmacology-antimicrobials/videos/medical-pharmacology-antimicrobials-antimycobacterials-leprosy-drugs?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical]
https://onlinemeded.org/spa/microbiology/antimycobacterials/acquire?ref=anki
Flashcard 37: Sulfa drugs are contraindicated in _____, as they can precipitate hemolytic anemia
Answer: G6PD deficiency
Extra:
Watch Trimethoprim/Sulfamethoxazole [https://dashboard.sketchy.com/study/medical/courses/medical-pharmacology/units/medical-pharmacology-antimicrobials/videos/medical-pharmacology-antimicrobials-other-antibiotics-trimethoprimsulfamethoxazole?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical]
https://onlinemeded.org/spa/infectious-disease?ref=anki
Flashcard 38: Which chemotherapeutic drug is used to treat pediatric (childhood) tumors?
_____
Answer: Actinomycin D
Extra:
Watch Bleomycin, doxorubicin, daunorubicin, actinomycin D [https://dashboard.sketchy.com/study/medical/courses/medical-pharmacology/units/medical-pharmacology-antineoplastics/videos/medical-pharmacology-antineoplastics-dna-and-cellular-division-bleomycin-doxorubicin-daunorubicin-actinomycin-d?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical]
https://onlinemeded.org?ref=anki
Flashcard 39: What structural feature of Penicillins give them their activity?
_____
Answer: B-lactam ring
Extra: The beta-lactam core of the molecule irreversibly binds (acetylates) a serine residue of the Transpeptidase active site. Acetylation of this site makes transpeptidases inactive, preventing cross-linking of the newly formed peptidoglycan layer.
Flashcard 40: Which Aminopenicillin is used as part of Helicobacter pylori triple therapy?
_____
Answer: Amoxicillin
Extra:
https://onlinemeded.org/spa/infectious-disease?ref=anki
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