Metabolism — Flashcards

What are the following substances? -Bisphosphoglycerate mutase -Hexokinase -Pyruvate kinase -Transketolase

What are the following amino acids? -Alanine -Aspartate -Histidine -Arginine -Glutamine

In what reaction Xylulose will be found?

11 y/o girl is evaluated for blurry vision. - Physical Exam: bilateral lens opacities -Urine is positive for reducing substances. -Deficient activity of which enzyme is the most likely cause of this patient's eye condition?

In what disease the followings are associated with? -Delta-Aminolevulinate dehydratase -Delta- Aminolevulinate synthase -Bilirubin glucuronyl transferase -Porphobilinogen deaminase -Uroporphyrinogen decarboxylase

what are the followings in relation to Phenylalanine metabolism? -Dihydrobiopterin reductase -Dopamine B-hydroxylase -Dopamine decarboxylase -Phenylalanine hydroxylase -Phenylethanolamine N-methyltransferase -Tyrosinase

12 y/o patient present with severe chest pain. -He has had intermittent substernal chest pain for past few months, occurs after heavy activity. -BP: 130/80   Pulse: 132/min     RR: 24/min -Physical exam: Anxious appearing boy with rapid but regular pulse. -Troponin is elevated. ECG reveals ST segment elevations in leads II, III, & aVF. -Further lab results: Increase serum methionine level. -Which amino acids is most likely essential in this patient?

6 month old full term boy comes with lethargy and vomiting. -Patient was breastfed exclusively until 2 days ago when homemade purred food was added to his diet. -Serum glucose: 30 mg/dL. -Dx: confirms aldolase B deficiency. What should be removed from this patient's diet?

3 day old boy comes with poor feeding, vomiting, and progressive lethargy. -Parents stated: "Diaper have burnt sugar smell" -Physical Exam: Lethargic infant with dry mucous membranes and generalized hypertonia. -Which of the following should be restricted from this infant's diet?

74 y/o woman comes with 2 days of left leg pain and numbness. -History of A. Fib & hypertension. -Left lower limb is pale & cold to palpation below the knee. -Ultrasound: occluding thrombus & a left femoral embolectomy is performed. -Post procedure dorsalis pedis & posterior tibial pulses become palpable. -Several hours later, patient feels severe left calf pain, with absent distal pulses. -Physican suspects: injury of the reperfused muscles due to overproduction of reactive oxygen species. -What enzymes is the most likely to help neutralize these toxic molecules?