Metabolism US Medical PG Flashcards - Medical Study Cards
Master Metabolism with OnCourse flashcards. These spaced repetition flashcards are designed for medical students preparing for NEET PG, USMLE Step 1, USMLE Step 2, MBBS exams, and other medical licensing examinations.
Metabolism Flashcard Deck - 10 Cards
Flashcard 701: What indicates a positive dihydrorhodamine flow cytometry test for CGD?\n_____
Answer: Minimal green fluorescence (lack of rhodamine)
Extra: Chronic Granulomatous Disease (CGD) is caused by a deficiency in NADPH oxidase. This leads to an inability to generate superoxide, which is required to oxidize dihydrorhodamine 123 into fluorescent rhodamine 123. Thus, a lack of fluorescence is diagnostic.
Flashcard 702: Corticosterone may be converted to _____ via the enzyme aldosterone synthase
Answer: aldosterone
Extra:
Watch Congenital Adrenal Hyperplasia (CAH) [https://dashboard.sketchy.com/study/medical/courses/medical-pathophysiology/units/medical-pathophysiology-endocrine/videos/medical-pathophysiology-endocrine-adrenal-disorders-congenital-adrenal-hyperplasia-cah?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical]
https://onlinemeded.org/spa/endocrinology/adrenals/acquire?ref=anki
Flashcard 703: Flavin nucleotides (FAD+) come from Vitamin _____
Answer: B2
Extra:
https://onlinemeded.org/spa/metabolism/pyruvate-dehydrogenase/acquire?ref=anki
Flashcard 704: The primary route of copper excretion from the body is via _____
Answer: bile
Extra: Copper is primarily excreted into the bile by the liver (mediated by ATP7B). This copper then enters the GI tract and is eliminated in the feces. Renal excretion is a minor pathway.
Flashcard 705: Phenylalanine may be converted to _____ via the enzyme phenylalanine hydroxylase (with tetrahydrobiopterin as a cofactor)
Answer: tyrosine
Extra:
https://onlinemeded.org/spa/dna-to-protein/amino-acids/acquire?ref=anki
Other:
BH4 = tetrahydrobiopterin
Flashcard 706: Electrons from complex III of the ETC are transferred to _____
Answer: cytochrome C
Extra:
Watch Electron Transport Chain (ETC)/Oxidative Phosphorylation [https://dashboard.sketchy.com/study/medical/courses/medical-biochemistry/units/medical-biochemistry-metabolism/videos/medical-biochemistry-metabolism-carbohydrates-electron-transport-chainoxidative-phosphorylation?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical]
https://onlinemeded.org/spa/metabolism/electron-transport-chain/acquire?ref=anki
Flashcard 707: Carcinoid tumors are characterized by increased excretion of _____ in the urine
Answer: 5-HIAA
Extra: Refer to endocrine section:
* "HI-AA": elevated urine 5-HIAA (5-hydroxyindolacetic acid), a breakdown product of serotonin, is diagnostic of carcinoid syndrome
Watch Carcinoid Tumor & Small Bowel Neoplasms [https://dashboard.sketchy.com/study/medical/courses/medical-pathophysiology/units/medical-pathophysiology-gi/videos/medical-pathophysiology-gi-small-bowel-disorders-carcinoid-tumor-and-small-bowel-neoplasms?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical] Watch associated Bootcamp video [https://app.bootcamp.com/med-school/gastroenterology/videos/intestinal-pathology?index=7]
https://onlinemeded.org/spa/gastroenterology/chronic-diarrhea/acquire?ref=anki
Atlas:
Flashcard 708: Thyroid Peroxidase is involved in the first part of T4 synthesis, specifically by catalyzing the addition of iodine to tyrosine residues on _____
Answer: thyroglobulin
Extra:
https://onlinemeded.org/spa/endocrinology/thyroid/acquire?ref=anki
Flashcard 709: Conversion of malate to pyruvate via malic enzyme produces a molecule of _____ (fatty acid synthesis)
Answer: NADPH
Extra:
Watch Fatty Acid Synthesis [https://dashboard.sketchy.com/study/medical/courses/medical-biochemistry/units/medical-biochemistry-metabolism/videos/medical-biochemistry-metabolism-lipids-fatty-acid-synthesis?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical]
https://onlinemeded.org/spa/metabolism?ref=anki
Flashcard 710: What uncoupling agent of oxidative phosphorylation is used illicitly for weight loss?
_____
Answer: 2,4-dinitrophenol (2,4-DNP)
Extra:
Watch Electron Transport Chain (ETC)/Oxidative Phosphorylation [https://dashboard.sketchy.com/study/medical/courses/medical-biochemistry/units/medical-biochemistry-metabolism/videos/medical-biochemistry-metabolism-carbohydrates-electron-transport-chainoxidative-phosphorylation?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical]
https://onlinemeded.org/spa/metabolism/electron-transport-chain/acquire?ref=anki
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