Metabolism — Flashcards

Flashcard 701: The primary route of copper excretion from the body is via _____

Answer: bile

Extra: Copper is primarily excreted into the bile by the liver (mediated by ATP7B). This copper then enters the GI tract and is eliminated in the feces. Renal excretion is a minor pathway.

Flashcard 702: Corticosterone may be converted to _____ via the enzyme aldosterone synthase

Answer: aldosterone

Flashcard 703: Thyroid Peroxidase is involved in the first part of T4 synthesis, specifically by catalyzing the addition of iodine to tyrosine residues on _____

Answer: thyroglobulin

Flashcard 704: Carcinoid tumors are characterized by increased excretion of _____ in the urine

Answer: 5-HIAA

Extra: Refer to endocrine section: * "HI-AA": elevated urine 5-HIAA (5-hydroxyindolacetic acid), a breakdown product of serotonin, is diagnostic of carcinoid syndrome Atlas:

Flashcard 705: Flavin nucleotides (FAD+) come from Vitamin _____

Answer: B2

Flashcard 706: Electrons from complex III of the ETC are transferred to _____

Answer: cytochrome C

Flashcard 707: Phenylalanine may be converted to _____ via the enzyme phenylalanine hydroxylase (with tetrahydrobiopterin as a cofactor)

Answer: tyrosine

Extra: Other: BH4 = tetrahydrobiopterin

Flashcard 708: Conversion of malate to pyruvate via malic enzyme produces a molecule of _____ (fatty acid synthesis)

Answer: NADPH

Flashcard 709: The clotting factor with the shortest half life is Factor _____, whereas the factor with the longest half life is Factor _____

Answer: VII

Flashcard 710: What uncoupling agent of oxidative phosphorylation is used illicitly for weight loss? _____

Answer: 2,4-dinitrophenol (2,4-DNP)