Metabolism — Flashcards

Flashcard 691: What enzyme is elevated in mumps patients due to involvement of the pancreatic or salivary glands? _____

Answer: α-amylase

Flashcard 692: Vitamin B2 (riboflavin) is a precursor to _____ and _____

Answer: FAD

Flashcard 693: What is the effect of uncoupling agents (ETC) on O2 consumption? _____

Answer: Increased

Flashcard 694: What do the carrier molecules NADH, NADPH, and FADH2 carry in their activated forms? _____

Answer: Electrons

Flashcard 695: Pure vegan diets (without calcium supplementation) may cause _____ kidney stones

Answer: calcium oxalate

Flashcard 696: 25-hydroxylase converts Vitamin D3 into _____

Answer: 25-hydroxyvitamin D (calcidiol)

Flashcard 697: Cystine kidney stones precipitate with _____ urine pH

Answer: low

Flashcard 698: Azathioprine and 6-mercaptopurine increase cellular levels of _____

Answer: PRPP

Flashcard 699: A deficiency in _____ is the most common genetic cause of hyperhomocysteinemia

Answer: methylene tetrahydrofolate reductase (MTHFR)

Flashcard 700: What indicates a positive dihydrorhodamine flow cytometry test for CGD?\n_____

Answer: Minimal green fluorescence (lack of rhodamine)

Extra: Chronic Granulomatous Disease (CGD) is caused by a deficiency in NADPH oxidase. This leads to an inability to generate superoxide, which is required to oxidize dihydrorhodamine 123 into fluorescent rhodamine 123. Thus, a lack of fluorescence is diagnostic.