Metabolism — Flashcards

Flashcard 681: UDP is converted to _____ via the enzyme ribonucleotide reductase (pyrimidine synthesis)

Answer: dUDP

Flashcard 682: Vitamin B12 and folate deficiency result in mildly elevated _____ levels, increasing risk for thrombosis

Answer: homocysteine

Flashcard 683: What is the most common cause of oxidative stress in patients with G6PD deficiency? _____

Answer: Infection

Extra: Other:

Flashcard 684: Binding of atrial natriuretic peptide to its receptor guanylyl cyclase causes conversion of _____ to _____

Answer: GTP

Flashcard 685: Treatment for phenylketonuria includes a diet low in _____ with supplemental tyrosine +/- tetrahydrobiopterin

Answer: phenylalanine

Flashcard 686: Inflammation of the lips with scaling and fissures at the corners of the mouth is known as _____

Answer: cheilosis

Flashcard 687: In _____, the respiratory burst is intact, and thus will produce superoxide (O-) and hydrogen peroxide (H2O2)

Answer: Myeloperoxidase deficiency (MPO)

Flashcard 688: TRH acts on which signalling cascade? _____

Answer: IP3

Flashcard 689: Upregulation of interferon synthesis in infected cells is accomplished by _____

Answer: double-stranded RNA (dsRNA)

Extra: Interferons (α, β) are part of the innate immune response and are synthesized by virus-infected cells in response to the presence of double-stranded RNA (dsRNA). Sketchy Pharmacology: GI (Hepatitis) Watch Interferon a, b, y

Flashcard 690: Conversion of malate into oxaloacetate produces a molecule of _____

Answer: NADH

Extra: Other: